PROS1 Protein (His tag)
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- Target See all PROS1 (PROS) Proteins
- PROS1 (PROS) (Protein S (PROS))
- Protein Type
- Recombinant
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Origin
- Human
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Source
- HEK-293 Cells
- Purification tag / Conjugate
- This PROS1 protein is labelled with His tag.
- Purpose
- Recombinant Human PROS1/Protein S Protein (His Tag)
- Sequence
- Met 1-Ser676
- Characteristics
- A DNA sequence encoding the human PROS1 (P07225) (Met1-Ser676) was expressed with a polyhistidine tag at the C-terminus.
- Purity
- > 95 % as determined by reducing SDS-PAGE.
- Endotoxin Level
- < 1.0 EU per μg as determined by the LAL method.
- Top Product
- Discover our top product PROS Protein
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- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Please refer to the printed manual for detailed information.
- Buffer
- Lyophilized from sterile PBS, pH 7.4
- Storage
- 4 °C,-20 °C,-80 °C
- Storage Comment
- Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
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- Target
- PROS1 (PROS) (Protein S (PROS))
- Alternative Name
- PROS1 (PROS Products)
- Synonyms
- PROS Protein, PS21 Protein, PS22 Protein, PS23 Protein, PS24 Protein, PS25 Protein, PSA Protein, THPH5 Protein, THPH6 Protein, zgc:154001 Protein, AW214361 Protein, protein S Protein, protein S (alpha) Protein, PROS1 Protein, Pros1 Protein, pros1 Protein
- Background
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Background: PROS1, also known as protein S, is a vitamin K-dependent plasma protein that functions as a cofactor for the anticoagulant protease, activated protein C (APC) to inhibit blood coagulation. PROS1 has two isoforms: a free, functionally active form and an inactive form complexed with C4b-binding protein. Besides its anticoagulant function, PROS1 also acts as an agonist for the tyrosine kinase receptors Tyro3, Axl, and Mer. The endothelium expresses Tyro3, Axl, and Mer and produces protein S. The interaction of protein S with endothelial cells and particularly its effects on angiogenesis have not yet been analyzed.
Synonym: PROS,Protein S,PS21,PS22,PS23,PS24,PS25,PSA,THPH5,THPH6
- Molecular Weight
- 74.1 kDa
- UniProt
- P07225
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