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PFN2 Protein

PFN2 Origin: Human Host: Escherichia coli (E. coli) Recombinant > 95 % as determined by reducing SDS-PAGE.
Catalog No. ABIN7318935
  • Target See all PFN2 Proteins
    PFN2 (Profilin 2 (PFN2))
    Protein Type
    Recombinant
    Origin
    • 6
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Human
    Source
    • 11
    • 3
    • 2
    • 1
    Escherichia coli (E. coli)
    Purpose
    Recombinant Human Profilin-2/PFN2 Protein
    Sequence
    Met 1-Phe140
    Characteristics
    Recombinant Human Profilin-2 is produced by our E.coli expression system and the target gene encoding Met1-Phe140 is expressed.
    Purity
    > 95 % as determined by reducing SDS-PAGE.
    Endotoxin Level
    < 1.0 EU per μg as determined by the LAL method.
    Top Product
    Discover our top product PFN2 Protein
  • Restrictions
    For Research Use only
  • Format
    Lyophilized
    Reconstitution
    Please refer to the printed manual for detailed information.
    Buffer
    Lyophilized from a 0.2 μm filtered solution of 20 mM Tris,150 mM NaCl, pH 8.0.
    Storage
    4 °C,-20 °C,-80 °C
    Storage Comment
    Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
  • Target
    PFN2 (Profilin 2 (PFN2))
    Alternative Name
    Profilin-2/PFN2 (PFN2 Products)
    Synonyms
    D3S1319E Protein, PFL Protein, Pfn Protein, Profilin2 Protein, XProfilin2 Protein, PFN2 Protein, PRO2 Protein, Profilin-2 Protein, pfl Protein, d3s1319e Protein, profilin-2 Protein, F17A13.170 Protein, F17A13_170 Protein, PRF2 Protein, PROFILIN Protein, PROFILIN 2 Protein, profilin 2 Protein, wu:fb01g08 Protein, wu:fb54f09 Protein, wu:fd58f06 Protein, profilin 2 Protein, profilin 2 L homeolog Protein, profilin homolog 2 Protein, Profilin-2 Protein, PFN2 Protein, Pfn2 Protein, pfn2.L Protein, prf2 Protein, pfn2 Protein, pfn-2 Protein
    Background

    Background: Profilin-II (PFN2) is ubiquitous protein which belongs to the profilin family. PFN2 binds to actin, thenaffects the structure of the cytoskeleton. At high concentrations, profiling prevents the polymerization of actin, while increases that at low concentrations. PFN2 is a ubiquitous actin monomer-binding protein. It regulates actin polymerization in response to extra cellular signals. PFN2 binds to PIP2, it inhibits the formation of IP3 and DG.

    Synonym: Profilin-II, PFN2, Profilin-2, PFL

    Molecular Weight
    15.0 kDa
    UniProt
    P35080
    Pathways
    Regulation of Actin Filament Polymerization, Synaptic Vesicle Exocytosis
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