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PMVK Protein (His tag)

PMVK Origin: Human Host: Escherichia coli (E. coli) Recombinant > 95 % as determined by reducing SDS-PAGE.
Catalog No. ABIN7318901
  • Target See all PMVK Proteins
    PMVK (Phosphomevalonate Kinase (PMVK))
    Protein Type
    Recombinant
    Origin
    • 5
    • 1
    • 1
    • 1
    Human
    Source
    • 2
    • 2
    • 2
    • 1
    • 1
    Escherichia coli (E. coli)
    Purification tag / Conjugate
    This PMVK protein is labelled with His tag.
    Purpose
    Recombinant Human Phosphomevalonate Kinase/PMVK Protein (His Tag)
    Sequence
    Met 1-Leu192
    Characteristics
    Recombinant Human Phosphomevalonate Kinase is produced by our E.coli expression system and the target gene encoding Met1-Leu192 is expressed with a 6His tag at the N-terminus.
    Purity
    > 95 % as determined by reducing SDS-PAGE.
    Endotoxin Level
    < 1.0 EU per μg as determined by the LAL method.
    Top Product
    Discover our top product PMVK Protein
  • Restrictions
    For Research Use only
  • Format
    Frozen, Liquid
    Buffer
    Supplied as a 0.2 μm filtered solution of 20 mM TrisHCl, 100 mM NaCl, 1 mM DTT, 10 % Glycerol, pH 7.5.
    Storage
    -20 °C
    Storage Comment
    Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles.
  • Target
    PMVK (Phosphomevalonate Kinase (PMVK))
    Alternative Name
    Phosphomevalonate Kinase/PMVK (PMVK Products)
    Synonyms
    MPK_Bm Protein, F5M6.9 Protein, F5M6_9 Protein, zgc:162701 Protein, HUMPMKI Protein, PMK Protein, PMKA Protein, PMKASE Protein, 1110011E12Rik Protein, 2900002L22Rik Protein, AV001327 Protein, phosphomevalonate kinase Protein, GHMP kinase family protein Protein, PMVK Protein, Mpk Protein, AT1G31910 Protein, CpipJ_CPIJ015413 Protein, Bm1_05275 Protein, pmvk Protein, LOAG_11811 Protein, Tsp_06629 Protein, LOC100282968 Protein, Pmvk Protein
    Background

    Background: Phosphomevalonate kinase (PMVK) is a cytosolic enzyme. PMVK can be highly expressed in the heart,skeletal muscle, liver, pancreas, and kidney, it is expressed at lower levels in the brain, lung, and placenta. Induced by sterol, PMVK takes part in isopentenyl diphosphate biosynthesis through the mevalonate pathway. PMVK catalyzes the conversion of mevalonate 5-phosphate into mevalonate 5-diphosphate in the fifth reaction of the cholesterol biosynthetic pathway.

    Synonym: Phosphomevalonate Kinase, PMKase, hPMK, PMVK, PMKI

    Molecular Weight
    24.2 kDa
    UniProt
    Q15126
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