PMVK Protein (His tag)
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- Target See all PMVK Proteins
- PMVK (Phosphomevalonate Kinase (PMVK))
- Protein Type
- Recombinant
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Origin
- Human
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Source
- Escherichia coli (E. coli)
- Purification tag / Conjugate
- This PMVK protein is labelled with His tag.
- Purpose
- Recombinant Human Phosphomevalonate Kinase/PMVK Protein (His Tag)
- Sequence
- Met 1-Leu192
- Characteristics
- Recombinant Human Phosphomevalonate Kinase is produced by our E.coli expression system and the target gene encoding Met1-Leu192 is expressed with a 6His tag at the N-terminus.
- Purity
- > 95 % as determined by reducing SDS-PAGE.
- Endotoxin Level
- < 1.0 EU per μg as determined by the LAL method.
- Top Product
- Discover our top product PMVK Protein
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- Restrictions
- For Research Use only
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- Format
- Frozen, Liquid
- Buffer
- Supplied as a 0.2 μm filtered solution of 20 mM TrisHCl, 100 mM NaCl, 1 mM DTT, 10 % Glycerol, pH 7.5.
- Storage
- -20 °C
- Storage Comment
- Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles.
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- Target
- PMVK (Phosphomevalonate Kinase (PMVK))
- Alternative Name
- Phosphomevalonate Kinase/PMVK (PMVK Products)
- Synonyms
- MPK_Bm Protein, F5M6.9 Protein, F5M6_9 Protein, zgc:162701 Protein, HUMPMKI Protein, PMK Protein, PMKA Protein, PMKASE Protein, 1110011E12Rik Protein, 2900002L22Rik Protein, AV001327 Protein, phosphomevalonate kinase Protein, GHMP kinase family protein Protein, PMVK Protein, Mpk Protein, AT1G31910 Protein, CpipJ_CPIJ015413 Protein, Bm1_05275 Protein, pmvk Protein, LOAG_11811 Protein, Tsp_06629 Protein, LOC100282968 Protein, Pmvk Protein
- Background
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Background: Phosphomevalonate kinase (PMVK) is a cytosolic enzyme. PMVK can be highly expressed in the heart,skeletal muscle, liver, pancreas, and kidney, it is expressed at lower levels in the brain, lung, and placenta. Induced by sterol, PMVK takes part in isopentenyl diphosphate biosynthesis through the mevalonate pathway. PMVK catalyzes the conversion of mevalonate 5-phosphate into mevalonate 5-diphosphate in the fifth reaction of the cholesterol biosynthetic pathway.
Synonym: Phosphomevalonate Kinase, PMKase, hPMK, PMVK, PMKI
- Molecular Weight
- 24.2 kDa
- UniProt
- Q15126
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