PMM2 Protein (His tag)
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- Target See all PMM2 Proteins
- PMM2 (Phosphomannomutase 2 (PMM2))
- Protein Type
- Recombinant
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Origin
- Human
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Source
- Escherichia coli (E. coli)
- Purification tag / Conjugate
- This PMM2 protein is labelled with His tag.
- Purpose
- Recombinant Human PMM2 Protein (His Tag)
- Sequence
- Met 1-Ser246
- Characteristics
- Recombinant Human Phosphomannomutase 2 is produced by our E.coli expression system and the target gene encoding Met1-Ser246 is expressed with a 6His tag at the C-terminus.
- Purity
- > 95 % as determined by reducing SDS-PAGE.
- Endotoxin Level
- < 1.0 EU per μg as determined by the LAL method.
- Top Product
- Discover our top product PMM2 Protein
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Phosphomannomutase 2 (PMM2) (AA 47-111) protein (GST tag)
PMM2 Origin: Human Host: Wheat germ Recombinant ELISA, WB, AP, AA
Phosphomannomutase 2 (PMM2) (AA 1-246) protein (GST tag)PMM2 Origin: Human Host: Wheat germ Recombinant ELISA, WB, AP, AA
Phosphomannomutase 2 (PMM2) protein (Myc-DYKDDDDK Tag)PMM2 Origin: Human Host: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
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- Restrictions
- For Research Use only
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- Format
- Frozen, Liquid
- Buffer
- Supplied as a 0.2 μm filtered solution of 20 mM TrisHCl, 150 mM NaCl, pH 8.0.
- Storage
- -20 °C
- Storage Comment
- Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles.
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- Target
- PMM2 (Phosphomannomutase 2 (PMM2))
- Alternative Name
- PMM2 (PMM2 Products)
- Synonyms
- cb626 Protein, zgc:56149 Protein, MGC82869 Protein, pmm2 Protein, CDG1 Protein, CDG1a Protein, CDGS Protein, PMI Protein, PMI1 Protein, PMM 2 Protein, AI585868 Protein, C86848 Protein, phosphomannomutase 2 Protein, phosphomannomutase 2 S homeolog Protein, pmm2 Protein, PMM2 Protein, pmm2.S Protein, PTRG_02815 Protein, Tsp_00480 Protein, Pmm2 Protein
- Background
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Background: Phosphomannomutase 2 (PMM2) is an enzyme that is a member of the highly variable methyltransferase superfamily. PMM2 is a cytoplasmic protein and catalyzes the isomerization of mannose 6-phosphate to mannose 1-phosphate.In addition, PMM2 involved in the synthesis of the GDP-mannose and dolichol-phosphate-mannose that required for a number of critical mannosyl transfer reactions. Defects in PMM2 can results in congenital disorder of glycosylation type 1A (CDG1A). Congenital disorders of glycosylation are metabolic deficiencies in glycoprotein biosynthesis that usually cause severe mental and psychomotor retardation.
Synonym: Phosphomannomutase 2, PMM 2, PMM2
- Molecular Weight
- 29.1 kDa
- UniProt
- O15305
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