PGD Protein (His tag)

Catalog No. ABIN7319375

Product Details

Target: PGD (Phosphogluconate Dehydrogenase (PGD))

Protein Type: Recombinant

Origin: Human

Source: Human Cells

Purification tag / Conjugate: This PGD protein is labelled with His tag.

Purpose: Recombinant Human PGD Protein (Human Cells, His Tag)

Sequence: Met 1-Ala483

Characteristics: Recombinant Human 6-phosphogluconate dehydrogenase is produced by our Mammalian expression system and the target gene encoding Met1-Ala483 is expressed with a 6His tag at the C-terminus.

Purity: > 90 % as determined by reducing SDS-PAGE.

Endotoxin Level: < 1.0 EU per μg as determined by the LAL method.

Application Details

Restrictions: For Research Use only

Handling

Format: Frozen, Liquid

Buffer: Supplied as a 0.2 μm filtered solution of 20 mM PB,150 mM NaCl, pH 7.4.

Storage: -20 °C

Storage Comment: Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles.

Target Details

Target: PGD (Phosphogluconate Dehydrogenase (PGD))

Alternative Name: PGD (PGD Products)

Background:

Background: 6-phosphogluconate dehydrogenase(PGD) is a cytoplasm-located protein, and belongs to the 6-phosphogluconate dehydrogenase family. 6PGD is the second dehydrogenase in the pentose phosphate shunt. It catalyzes the oxidative decarboxylation of 6-phosphogluconate to ribulose 5-phosphate and CO2, with concomitant reduction of NADP to NADPH. Mutations within the gene coding this enzyme result in 6-phosphogluconate dehydrogenase deficiency, an autosomal hereditary disease effecting the red blood cells.

Synonym: 6-phosphogluconate dehydrogenase, Decarboxylating,PGD,PGDH,6PGD

Molecular Weight: 54.2 kDa

UniProt: P52209