PGD Protein (His tag)

Catalog No. ABIN7319375

Product Details

Target: PGD (Phosphogluconate Dehydrogenase (PGD))

Protein Type: Recombinant

Origin: Human

Source: Human Cells

Purification tag / Conjugate: This PGD protein is labelled with His tag.

Purpose: Recombinant Human PGD Protein (Human Cells, His Tag)

Sequence: Met 1-Ala483

Characteristics: Recombinant Human 6-phosphogluconate dehydrogenase is produced by our Mammalian expression system and the target gene encoding Met1-Ala483 is expressed with a 6His tag at the C-terminus.

Purity: > 90 % as determined by reducing SDS-PAGE.

Endotoxin Level: < 1.0 EU per μg as determined by the LAL method.

Application Details

Restrictions: For Research Use only

Handling

Format: Frozen, Liquid

Buffer: Supplied as a 0.2 μm filtered solution of 20 mM PB,150 mM NaCl, pH 7.4.

Storage: -20 °C

Storage Comment: Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles.

Target Details

Target: PGD (Phosphogluconate Dehydrogenase (PGD))

Alternative Name: PGD (PGD Products)

Synonyms: 6PGD Protein, 6-PGD Protein, 6-Pgd Protein, 6-pgd Protein, 6PGDH Protein, 6Pgd Protein, 6Pgdh Protein, 6pgdh Protein, A7 Protein, CG3724 Protein, Dmel\\CG3724 Protein, EG:87B1.4 Protein, N1 Protein, PGD Protein, Pdg Protein, l(1)2Dc Protein, l(1)2De Protein, l(1)A7 Protein, l(1)G0385 Protein, l(1)N1 Protein, l(1)N3[90] Protein, l(1)Pgd Protein, l(1)Pgd-A Protein, l35 Protein, pgd Protein, 0610042A05Rik Protein, AU019875 Protein, C78335 Protein, fi03d03 Protein, zgc:55585 Protein, wu:fi03d03 Protein, zgc:111848 Protein, 6-PGDH Protein, GND1b Protein, Pgd Protein, Cc2-27 Protein, phosphogluconate dehydrogenase Protein, Phosphogluconate dehydrogenase Protein, phosphogluconate dehydrogenase L homeolog Protein, 6-phosphogluconate dehydrogenase, decarboxylating Protein, 6-phosphogluconate dehydrogenase, decarboxylating-like Protein, PGD Protein, Pgd Protein, pgd.L Protein, pgd Protein, GND1a|GND1b Protein, Thal_1580 Protein, GY4MC1_3101 Protein, Odosp_2189 Protein, Marky_1024 Protein, gnd Protein, LOC101451876 Protein

Background:

Background: 6-phosphogluconate dehydrogenase(PGD) is a cytoplasm-located protein, and belongs to the 6-phosphogluconate dehydrogenase family. 6PGD is the second dehydrogenase in the pentose phosphate shunt. It catalyzes the oxidative decarboxylation of 6-phosphogluconate to ribulose 5-phosphate and CO2, with concomitant reduction of NADP to NADPH. Mutations within the gene coding this enzyme result in 6-phosphogluconate dehydrogenase deficiency, an autosomal hereditary disease effecting the red blood cells.

Synonym: 6-phosphogluconate dehydrogenase, Decarboxylating,PGD,PGDH,6PGD

Molecular Weight: 54.2 kDa

UniProt: P52209