Peroxiredoxin 5 Protein (PRDX5) (His tag)

Catalog No. ABIN7318892

Product Details

Target: Peroxiredoxin 5 (PRDX5)

Protein Type: Recombinant

Origin: Human

Source: Human Cells

Purification tag / Conjugate: This Peroxiredoxin 5 protein is labelled with His tag.

Purpose: Recombinant Human Peroxiredoxin 5/PRDX5 Protein (His Tag)

Sequence: Met53-Leu214

Characteristics: Recombinant Human Peroxiredoxin-5 is produced by our Mammalian expression system and the target gene encoding Met53-Leu214 is expressed with a 6His tag at the N-terminus.

Purity: > 95 % as determined by reducing SDS-PAGE.

Endotoxin Level: < 1.0 EU per μg as determined by the LAL method.

Application Details

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Please refer to the printed manual for detailed information.

Buffer: Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4.

Storage: 4 °C,-20 °C,-80 °C

Storage Comment: Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.

Target Details

Target: Peroxiredoxin 5 (PRDX5)

Alternative Name: Peroxiredoxin 5/PRDX5 (PRDX5 Products)

Synonyms: acr1 Protein, aoeb166 Protein, pmp20 Protein, prx-5 Protein, prx5 Protein, prxv Protein, sbbi10 Protein, GB16965 Protein, zgc:112318 Protein, PRDX5 Protein, CG 32920 Protein, CG 7217 Protein, CG32920 Protein, CG7217 Protein, Dmel\\CG7217 Protein, dPrx5 Protein, dprx5 Protein, ACR1 Protein, AOEB166 Protein, B166 Protein, PLP Protein, PMP20 Protein, PRDX6 Protein, PRXV Protein, prx-V Protein, AOPP Protein, Pmp20 Protein, Prdx6 Protein, PrxV Protein, Aoeb166 Protein, Prx V Protein, peroxiredoxin 5 L homeolog Protein, peroxiredoxin-5, mitochondrial Protein, peroxiredoxin 5 Protein, Peroxiredoxin 5 Protein, prdx5.L Protein, LOC552429 Protein, prdx5 Protein, PRDX5 Protein, Prx5 Protein, Prdx5 Protein

Background:

Background: Peroxisomes are essential organelles that participate in multiple important metabolic processes, including the β-oxidation of fatty acids, plasmalogen synthesis, and the metabolism of reactive oxygen species (ROS). Peroxiredoxins is overexpressed in breast cancer tissues to a great extent suggesting that they has a proliferative effect and may be related to cancer development or progression. Peroxiredoxin 5 (PRDX5) is a thioredoxin peroxidase that belongs to the atypical 2-Cys class of the TSA/ahpC family of peroxiredoxins. PRDX5 is a widely expressed mitochondrial antioxidant enzyme that reduces hydrogen peroxide, alkyl hydroperoxides, and peroxynitrite. In human cells, this enzyme is present in the cytosol, mitochondria, peroxisomes, and nucleus.

Synonym: Peroxiredoxin-5, PRDX5, Alu corepressor 1, Antioxidant enzyme B166, AOEB166, Liver tissue 2D-page spot 71B, PLP, Peroxiredoxin V, Prx-V, Peroxisomal antioxidant enzyme, TPx type VI, Thioredoxin peroxidase PMP20, Thioredoxin reductase

Molecular Weight: 17.9 kDa

UniProt: P30044

Pathways: Cell RedoxHomeostasis