Peroxiredoxin 4 Protein (PRDX4) (His tag)
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- Target See all Peroxiredoxin 4 (PRDX4) Proteins
- Peroxiredoxin 4 (PRDX4)
- Protein Type
- Recombinant
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Origin
- Human
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Source
- Escherichia coli (E. coli)
- Purification tag / Conjugate
- This Peroxiredoxin 4 protein is labelled with His tag.
- Purpose
- Recombinant Human Peroxiredoxin-4/PRDX4 Protein (His Tag)
- Sequence
- Trp38-Asn271
- Characteristics
- Recombinant Human Peroxiredoxin-4 is produced by our E.coli expression system and the target gene encoding Trp38-Asn271 is expressed with a 6His tag at the N-terminus.
- Purity
- > 95 % as determined by reducing SDS-PAGE.
- Endotoxin Level
- < 1.0 EU per μg as determined by the LAL method.
- Top Product
- Discover our top product PRDX4 Protein
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- Restrictions
- For Research Use only
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- Format
- Frozen, Liquid
- Buffer
- Supplied as a 0.2 μm filtered solution of 20 mM PB, 150 mM NaCl, 1 mM DTT, pH 7.2.
- Storage
- -20 °C
- Storage Comment
- Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles.
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- Target
- Peroxiredoxin 4 (PRDX4)
- Alternative Name
- Peroxiredoxin-4/PRDX4 (PRDX4 Products)
- Synonyms
- MGC82793 Protein, prdx4 Protein, MGC79732 Protein, PRDX4 Protein, AOE37-2 Protein, PRX-4 Protein, AOE372 Protein, Prx-iv Protein, Prx4 Protein, TRANK Protein, fb59c09 Protein, wu:fb59c09 Protein, zgc:162938 Protein, peroxiredoxin 4 Protein, peroxiredoxin 4 L homeolog Protein, PRDX4 Protein, prdx4.L Protein, prdx4 Protein, Prdx4 Protein
- Background
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Background: Peroxiredoxin-4 (PRDX4) is a member of the AhpC/TSA family. PRDX4 is a cytoplasmic protein and contains one thioredoxin domain. PRDX4 exists in homodimer or heterodimer with PRDX1. PRDX4 reduces hydrogen peroxide and alkyl hydroperoxides to water and alcohol with the use of reducing equivalents derived from thiol-containing donor molecules. In addition, PRDX4 is probably involved in redox regulation of the cell, regulating the activation of NF-kappa-B in the cytosol by a modulation of I-kappa-B-alpha phosphorylation.
Synonym: Peroxiredoxin-4, Antioxidant Enzyme AOE372, AOE37-2, Peroxiredoxin IV, Prx-IV, Thioredoxin Peroxidase AO372, Thioredoxin-Dependent Peroxide Reductase A0372, PRDX4
- Molecular Weight
- 33.8 kDa
- UniProt
- Q13162
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