Peroxiredoxin 1 Protein (PRDX1) (His tag)
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- Target See all Peroxiredoxin 1 (PRDX1) Proteins
- Peroxiredoxin 1 (PRDX1)
- Protein Type
- Recombinant
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Origin
- Mouse
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Source
- Escherichia coli (E. coli)
- Purification tag / Conjugate
- This Peroxiredoxin 1 protein is labelled with His tag.
- Purpose
- Recombinant Mouse Peroxiredoxin 1/PRDX1 Protein (His Tag)
- Sequence
- Met 1-Lys 199
- Characteristics
- A DNA sequence encoding the mouse PRDX1 (P35700) (Met 1-Lys 199) was expressed, with a C-terminal polyhistidine tag.
- Purity
- > 85 % as determined by SDS-PAGE
- Top Product
- Discover our top product PRDX1 Protein
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Peroxiredoxin 1 (PRDX1) (AA 1-199) protein (GST tag)
PRDX1 Origin: Human Host: Wheat germ Recombinant WB, ELISA, AP, AA
Peroxiredoxin 1 (PRDX1) (AA 1-199), (full length) protein (GST tag)PRDX1 Origin: Human Host: Escherichia coli (E. coli) Recombinant 95 % ELISA
Peroxiredoxin 1 (PRDX1) proteinPRDX1 Origin: Mouse Host: Escherichia coli (E. coli) Recombinant > 95 % SDS, WB, ELISA, IP
Peroxiredoxin 1 (PRDX1) (AA 1-199) (Active) protein (His tag)PRDX1 Origin: Mouse Host: Baculovirus infected Insect Cells Recombinant > 90 % by SDS - PAGE SDS Active
Peroxiredoxin 1 (PRDX1) (Transcript Variant 3) protein (Myc-DYKDDDDK Tag)PRDX1 Origin: Human Host: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
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- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Please refer to the printed manual for detailed information.
- Buffer
- Lyophilized from sterile PBS, 10 % glycerol, pH 7.4
- Storage
- 4 °C,-20 °C,-80 °C
- Storage Comment
- Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
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- Target
- Peroxiredoxin 1 (PRDX1)
- Alternative Name
- Peroxiredoxin 1/PRDX1 (PRDX1 Products)
- Background
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Background: Peroxiredoxin-1, also known as Thioredoxin peroxidase 2, Natural killer cell-enhancing factor A, PRDX1, and PAGA, is a member of the ahpC/TSA family. Peroxiredoxin-1 is constitutively expressed in most human cells. It is induced to higher levels upon serum stimulation in untransformed and transformed cells. Peroxiredoxins (PRDXs) are a family of antioxidant enzymes that are also known as scavengers of peroxide in mammalian cells. The overexpression of Peroxiredoxin-1, which is one of the peroxiredoxins that is a ubiquitously expressed protein, was related to a poor prognosis in several types of human cancers. Peroxiredoxin-1 is involved in redox regulation of the cell. It reduces peroxides with reducing equivalents provided through the thioredoxin system but not from glutaredoxin and may play an important role in eliminating peroxides generated during metabolism. Peroxiredoxin-1 Might participate in the signaling cascades of growth factors and tumor necrosis factor-alpha by regulating the intracellular concentrations of H2O2. The reduced Peroxiredoxin-1 expression is an important factor in esophageal squamous cancer progression and could serve as a useful prognostic marker.
Synonym: MSP23,NkefA,OSF-3,OSF3,PAG,Paga,PrdxI,prx1,PrxI,Tdpx2,TDX2,TPxA
- Molecular Weight
- 23.5 kDa
- UniProt
- P35700
- Pathways
- p53 Signaling, EGFR Signaling Pathway, CXCR4-mediated Signaling Events
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