Peroxiredoxin 1 Protein (PRDX1) (His tag)
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- Target See all Peroxiredoxin 1 (PRDX1) Proteins
- Peroxiredoxin 1 (PRDX1)
- Protein Type
- Recombinant
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Origin
- Human
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Source
- Escherichia coli (E. coli)
- Purification tag / Conjugate
- This Peroxiredoxin 1 protein is labelled with His tag.
- Purpose
- Recombinant Human Peroxiredoxin 1/PRDX1 Protein (His Tag)
- Sequence
- Met 1-Lys199
- Characteristics
- Recombinant Human Peroxiredoxin-1 is produced by our E.coli expression system and the target gene encoding Met1-Lys199 is expressed with a 6His tag at the N-terminus, 6His tag at the C-terminus.
- Purity
- > 95 % as determined by reducing SDS-PAGE.
- Endotoxin Level
- < 1.0 EU per μg as determined by the LAL method.
- Top Product
- Discover our top product PRDX1 Protein
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Peroxiredoxin 1 (PRDX1) (AA 1-199) protein (GST tag)
PRDX1 Origin: Human Host: Wheat germ Recombinant WB, ELISA, AP, AA
Peroxiredoxin 1 (PRDX1) protein (His tag)PRDX1 Origin: Mouse Host: Escherichia coli (E. coli) Recombinant > 85 % as determined by SDS-PAGE
Peroxiredoxin 1 (PRDX1) (AA 1-199), (full length) protein (GST tag)PRDX1 Origin: Human Host: Escherichia coli (E. coli) Recombinant 95 % ELISA
Peroxiredoxin 1 (PRDX1) proteinPRDX1 Origin: Mouse Host: Escherichia coli (E. coli) Recombinant > 95 % SDS, WB, ELISA, IP
Peroxiredoxin 1 (PRDX1) (AA 1-199) (Active) protein (His tag)PRDX1 Origin: Mouse Host: Baculovirus infected Insect Cells Recombinant > 90 % by SDS - PAGE SDS Active
Peroxiredoxin 1 (PRDX1) (Transcript Variant 3) protein (Myc-DYKDDDDK Tag)PRDX1 Origin: Human Host: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
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- Restrictions
- For Research Use only
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- Format
- Frozen, Liquid
- Buffer
- Supplied as a 0.2 μm filtered solution of PBS, 10 % glycerol, 0.1 mM DTT, pH 6.0.
- Storage
- -20 °C
- Storage Comment
- Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles.
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- Target
- Peroxiredoxin 1 (PRDX1)
- Alternative Name
- Peroxiredoxin 1/PRDX1 (PRDX1 Products)
- Synonyms
- MSP23 Protein, NKEF-A Protein, NKEFA Protein, PAG Protein, PAGA Protein, PAGB Protein, PRX1 Protein, PRXI Protein, TDPX2 Protein, NkefA Protein, OSF-3 Protein, OSF3 Protein, Paga Protein, PrdxI Protein, PrxI Protein, TDX2 Protein, TPxA Protein, Tdpx2 Protein, prx1 Protein, Hbp23 Protein, MGC80194 Protein, MGC84820 Protein, PRDX1 Protein, msp23 Protein, nkefa Protein, pag Protein, paga Protein, pagb Protein, prx-1 Protein, prxi Protein, tdpx2 Protein, hm:zehl0637 Protein, zgc:110343 Protein, TPX-2 Protein, peroxiredoxin 1 Protein, peroxiredoxin 1 S homeolog Protein, peroxiredoxin-1 pseudogene Protein, PRDX1 Protein, Prdx1 Protein, prdx1.S Protein, prdx1 Protein, LOC100350232 Protein
- Background
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Background: Peroxiredoxin-1(PRDX1) contains 1 thioredoxin domain and belongs to the AhpC/TSA family. PRDX1 constitutively expressed in most human cells and it is induced to higher levels upon serum stimulation in untransformed and transformed cells. PRDX1 is involved in redox regulation of the cell. It reduces peroxides with reducing equivalents provided through the thioredoxin system but not from glutaredoxin and play an important role in eliminating peroxides generated during metabolism. PRDX1 might participate in the signaling cascades of growth factors and tumor necrosis factor-alpha by regulating the intracellular concentrations of H2O2. It reduces an intramolecular disulfide bond in GDPD5 that gates the ability to GDPD5 to drive postmitotic motor neuron differentiation. It may contribute to the antiviral activity of CD8(+) T-cells and have a proliferative effect in cancer development or progression.
Synonym: Peroxiredoxin-1,Natural killer cell-enhancing factor A,NKEF-A,Proliferation-associated gene protein,PAG,Thioredoxin peroxidase 2,Thioredoxin-dependent peroxide reductase 2,PAGA, PAGB, TDPX2,MSP23,NKEF-A,NKEFA,PAG,PRX1,PRXI,TDPX2
- Molecular Weight
- 25.3 kDa
- UniProt
- Q06830
- Pathways
- p53 Signaling, EGFR Signaling Pathway, CXCR4-mediated Signaling Events
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