Parvin alpha Protein (His tag)
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- Target See all Parvin alpha (PARVA) Proteins
- Parvin alpha (PARVA) (Parvin, alpha (PARVA))
- Protein Type
- Recombinant
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Origin
- Human
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Source
- Escherichia coli (E. coli)
- Purification tag / Conjugate
- This Parvin alpha protein is labelled with His tag.
- Purpose
- Recombinant Human Alpha-Parvin/PARVA Protein (His Tag)
- Sequence
- Met 1-Glu372
- Characteristics
- Recombinant Human alpha-Parvin is produced by our E.coli expression system and the target gene encoding Met1-Glu372 is expressed with a 6His tag at the C-terminus.
- Purity
- > 85 % as determined by reducing SDS-PAGE.
- Endotoxin Level
- < 1.0 EU per μg as determined by the LAL method.
- Top Product
- Discover our top product PARVA Protein
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- Restrictions
- For Research Use only
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- Format
- Frozen, Liquid
- Buffer
- Supplied as a 0.2 μm filtered solution of 50 mM Tris, 150 mM NaCl, 40 % Glycerol, pH 7.4.
- Storage
- -20 °C
- Storage Comment
- Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles.
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- Target
- Parvin alpha (PARVA) (Parvin, alpha (PARVA))
- Alternative Name
- Alpha-Parvin/PARVA (PARVA Products)
- Synonyms
- CH-ILKBP Protein, MXRA2 Protein, Actp Protein, 2010012A22Rik Protein, 5430400F08Rik Protein, AI225929 Protein, AU042898 Protein, Parvin Protein, parva Protein, wu:fc59e06 Protein, zgc:101643 Protein, PARVA Protein, Parva Protein, parvin alpha Protein, parvin, alpha Protein, parvin, alpha a Protein, PARVA Protein, Parva Protein, parvaa Protein
- Background
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Background: Alpha-Parvin (PARVA) is a member of the Parvin family. PARVA contains two CH (calponin-homology) domains. PARVA is widely expressed, with highest levels in heart, skeletal muscle, kidney and liver. PARVA interacts with integrin-linked protein kinase and probably with actin and the LD1 and LD4 motifs of PXN. PARVA may play a role in the regulation of cell adhesion and cytoskeleton organization. PARVA is also involved in ciliogenesis.
Synonym: Alpha-Parvin, Actopaxin, CH-ILKBP, Calponin-Like Integrin-Linked Kinase-Binding Protein, Matrix-Remodeling-Associated Protein 2, PARVA, MXRA2
- Molecular Weight
- 43.2 kDa
- UniProt
- Q9NVD7
- Pathways
- Smooth Muscle Cell Migration
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