Otolin 1 Protein (OTOL1) (His tag)
OTOL1
Origin: Human
Host: Human Cells
Recombinant
>95 % as determined by reducing SDS-PAGE.
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- Target See all Otolin 1 (OTOL1) products
- Otolin 1 (OTOL1)
- Protein Type
- Recombinant
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Origin
- Human
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Source
- Human Cells
- Purification tag / Conjugate
- This Otolin 1 protein is labelled with His tag.
- Purpose
- Recombinant Human Otolin-1 (C-6His)
- Sequence
- Lys24-Pro477
- Characteristics
- Recombinant Human Otolin-1 is produced by our Mammalian expression system and the target gene encoding Lys24-Pro477 is expressed with a 6His tag at the C-terminus.
- Purity
- >95 % as determined by reducing SDS-PAGE.
- Endotoxin Level
- < 1.0 EU per μg as determined by the LAL method.
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- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Please refer to the printed manual for detailed information.
- Buffer
- Lyophilized from a 0.2 μm filtered solution of PBS, 5 % Trehalose, pH 7.4.
- Storage
- 4 °C,-20 °C,-80 °C
- Storage Comment
- Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
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- Target
- Otolin 1 (OTOL1)
- Alternative Name
- Otolin-1 (OTOL1 Products)
- Synonyms
- C1QTNF15 Protein, Gm414 Protein, otol1 Protein, si:dkey-119f1.2 Protein, zOtolin1 Protein, otolin 1 Protein, otolin 1a Protein, OTOL1 Protein, Otol1 Protein, otol1a Protein
- Background
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Background: Otolin (OTOL1), also known as C1qTNF15, is an approximately 65 kDa protein found in the otoconial membrane lining the cochlea and vestibular labyrinth of the inner ear. Collagen-like protein specifically expressed in the inner ear, which provides an organic scaffold for otoconia, a calcium carbonate structure in the saccule and utricle of the ear. It associates into multimers and disulfide-linked oligomers and also associates with other otoconial proteins including and Otoconin-90 (also known as PLA2G2A, PLA2L, and phospholipase A2 homolog) and Cerebellin-1. It is extensively glycosylated and has multiple hydroxylated proline residues in the collagenous regions.
Synonym: OTOL1, otolin 1, Otolin-1, C1qTNF15
- Molecular Weight
- 47.7 kDa
- UniProt
- A6NHN0
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