NUCB2 Protein
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- Target See all NUCB2 Proteins
- NUCB2 (Nucleobindin 2 (NUCB2))
- Protein Type
- Recombinant
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Origin
- Human
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Source
- Escherichia coli (E. coli)
- Purpose
- Recombinant Human Nucleobindin-2/NUCB2 Protein
- Sequence
- Val25-Leu106
- Characteristics
- Recombinant Human Nucleobindin-2 is produced by our E.coli expression system and the target gene encoding Val25-Leu106 is expressed.
- Purity
- > 95 % as determined by reducing SDS-PAGE.
- Endotoxin Level
- < 1.0 EU per μg as determined by the LAL method.
- Top Product
- Discover our top product NUCB2 Protein
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- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Please refer to the printed manual for detailed information.
- Buffer
- Lyophilized from a 0.2 μm filtered solution of 10 mM Sodium Phosphate, pH 6.5.
- Storage
- 4 °C,-20 °C,-80 °C
- Storage Comment
- Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
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- Target
- NUCB2 (Nucleobindin 2 (NUCB2))
- Alternative Name
- Nucleobindin-2/NUCB2 (NUCB2 Products)
- Synonyms
- nefa Protein, MGC97715 Protein, NUCB2 Protein, nucleobindin-2 Protein, NEFA Protein, AI607786 Protein, Calnuc Protein, Nefa Protein, Nesfatin-1 Protein, p54 Protein, nucleobindin 2 Protein, nucleobindin 2 L homeolog Protein, nucb2 Protein, NUCB2 Protein, Nucb2 Protein, nucb2.L Protein
- Background
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Background: Nesfatin-1 is a metabolic polypeptide encoded in the N-terminal region of the precursor protein, Nucleobindin2 (NUCB2). Nesfatin-1 is a neuropeptide produced in the hypothalamus of mammals. It participates in the regulation of hunger and fat storage. Nesfatin-1 is also expressed in other areas of the brain, and in pancreatic islets β-cells, gastric endocrine cells and adipocytes. Nesfatin-1 suppresses food intake and can regulate energy metabolism in a Leptin independent manner. Nesfatin-1 may also exert hypertensive roles and modulate blood pressure through directly acting on peripheral arterial resistance.
Synonym: Nucleobindin-2, DNA-binding protein NEFA, Gastric cancer antigen Zg4, Prepronesfatin, Nesfatin-1, NUCB2, NEFA
- Molecular Weight
- 9.6 kDa
- UniProt
- P80303
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