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NCF2 Protein

NCF2 Origin: Human Host: Baculovirus infected Insect Cells Recombinant > 85 % as determined by reducing SDS-PAGE.
Catalog No. ABIN7317174
  • Target See all NCF2 Proteins
    NCF2 (Neutrophil Cytosolic Factor 2 (NCF2))
    Protein Type
    Recombinant
    Origin
    • 7
    • 3
    • 1
    Human
    Source
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    Baculovirus infected Insect Cells
    Purpose
    Recombinant Human NCF2/P67phox Protein
    Sequence
    Met 1-Val526
    Characteristics
    A DNA sequence encoding the human NCF2 (AAH01606.1) (Met1-Val526) was expressed and purified with two additional amino acids (Gly & Pro) at the N-terminus.
    Purity
    > 85 % as determined by reducing SDS-PAGE.
    Endotoxin Level
    < 1.0 EU per μg as determined by the LAL method.
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  • Restrictions
    For Research Use only
  • Format
    Lyophilized
    Reconstitution
    Please refer to the printed manual for detailed information.
    Buffer
    Lyophilized from sterile 20 mM Tris, 300 mM NaCl, pH 8.0
    Storage
    4 °C,-20 °C,-80 °C
    Storage Comment
    Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
  • Target
    NCF2 (Neutrophil Cytosolic Factor 2 (NCF2))
    Alternative Name
    NCF2/P67phox (NCF2 Products)
    Synonyms
    MGC81877 Protein, zgc:158405 Protein, noxa2 Protein, p67-phox Protein, p67phox Protein, NCF-2 Protein, NOXA2 Protein, P67-PHOX Protein, P67PHOX Protein, Ncf-2 Protein, neutrophil cytosolic factor 2 Protein, neutrophil cytosolic factor 2 L homeolog Protein, neutrophil cytosol factor 2 Protein, hypothetical protein Protein, NCF2 Protein, ncf2.L Protein, ncf2 Protein, p67phox Protein, VDBG_06643 Protein, PGTG_05816 Protein, LOC100136240 Protein, Ncf2 Protein
    Background

    Background: NCF2, also known as NCF-2 and p67phox, is a subunit of the multi-protein NADPH oxidase complex. NCF2, NCF1, and a membrane bound cytochrome b558 are required for activation of the latent NADPH oxidase. This oxidase produces a burst of superoxide which is delivered to the lumen of the neutrophil phagosome. Mutations in NCF2 gene, as well as in other NADPH oxidase subunits, can result in chronic granulomatous disease, a disease that causes recurrent infections by catalase-positive organisms.

    Synonym: NCF-2,NOXA2,P67-PHOX,P67PHOX

    Molecular Weight
    59.9 kDa
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