NCALD Protein (His tag)
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- Target See all NCALD Proteins
- NCALD (Neurocalcin delta (NCALD))
- Protein Type
- Recombinant
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Origin
- Human
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Source
- Escherichia coli (E. coli)
- Purification tag / Conjugate
- This NCALD protein is labelled with His tag.
- Purpose
- Recombinant Human Neurocalcin-δ/NCALD Protein (His Tag)
- Sequence
- Met 1-Phe193
- Characteristics
- Recombinant Human Neurocalcin-delta is produced by our E.coli expression system and the target gene encoding Met1-Phe193 is expressed with a 6His tag at the N-terminus.
- Purity
- > 90 % as determined by reducing SDS-PAGE.
- Endotoxin Level
- < 1.0 EU per μg as determined by the LAL method.
- Top Product
- Discover our top product NCALD Protein
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- Restrictions
- For Research Use only
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- Format
- Frozen, Liquid
- Buffer
- Supplied as a 0.2 μm filtered solution of 20 mM TrisHCl, 100 mM NaCl, 1 mM DTT, 40 % Glycerol, pH 8.0.
- Storage
- -20 °C
- Storage Comment
- Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles.
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- Target
- NCALD (Neurocalcin delta (NCALD))
- Alternative Name
- Neurocalcin-delta/NCALD (NCALD Products)
- Synonyms
- AI848120 Protein, D030020D09Rik Protein, D15Ertd412e Protein, nca Protein, NCALD Protein, zgc:175182 Protein, ncald Protein, zgc:100982 Protein, neurocalcin delta Protein, neurocalcin delta L homeolog Protein, Neurocalcin delta Protein, neurocalcin delta a Protein, neurocalcin delta b Protein, Ncald Protein, NCALD Protein, ncald.L Protein, Bm1_53910 Protein, LOAG_16127 Protein, ncald Protein, ncalda Protein, ncaldb Protein
- Background
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Background: Neurocalcin-delta (NCALD) is a neuronal calcium-binding protein that belongs to the neuronal calcium sensor (NCS) family. It expressed in mammalian brains. NCALD contains an N-terminal myristoylation signal and four EF-hand calcium binding loops. The protein possesses a Ca2+ /myristoyl switch. It is cytosolic at resting calcium levels. However, elevated intracellular calcium levels induce a conformational change which exposes the myristoyl group, resulting in protein association with membranes and partial co-localization with the perinuclear trans-golgi network. NCALD protein is thought to be a regulator of G protein-coupled receptor signal transduction.
Synonym: Neurocalcin-Delta, NCALD
- Molecular Weight
- 24.4 kDa
- UniProt
- P61601
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