LC3B Protein

Catalog No. ABIN7319522

Product Details

Target: LC3B (MAP1LC3B) (Microtubule-Associated Protein 1 Light Chain 3 beta (MAP1LC3B))

Protein Type: Recombinant

Origin: Human

Source: Escherichia coli (E. coli)

Purpose: Recombinant Human MAP1LC3B Protein

Sequence: Met1-Val125

Characteristics: Recombinant Human MAP1LC3B is produced by our E.coli expression system and the target gene encoding Met1-Val125 is expressed.

Purity: > 95 % as determined by reducing SDS-PAGE.

Endotoxin Level: < 1.0 EU per μg as determined by the LAL method.

Application Details

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Please refer to the printed manual for detailed information.

Buffer: Lyophilized from a 0.2 μm filtered solution of 20 mM Tris, 150 mM NaCl, 2 mM DTT, pH 8.0.

Storage: 4 °C,-20 °C,-80 °C

Storage Comment: Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.

Target Details

Target: LC3B (MAP1LC3B) (Microtubule-Associated Protein 1 Light Chain 3 beta (MAP1LC3B))

Alternative Name: MAP1LC3B (MAP1LC3B Products)

Synonyms: ATG8F Protein, LC3B Protein, MAP1A/1BLC3 Protein, MAP1LC3B-a Protein, Map1lc3 Protein, Mpl3 Protein, zbs559 Protein, 1010001C15Rik Protein, Atg8 Protein, LC3b Protein, zgc:56434 Protein, wu:fb60g11 Protein, map1lc3b Protein, MGC76283 Protein, MAP1LC3B Protein, microtubule associated protein 1 light chain 3 beta Protein, microtubule-associated protein 1 light chain 3 beta Protein, microtubule associated protein 1 light chain 3 beta L homeolog Protein, MAP1LC3B Protein, Map1lc3b Protein, map1lc3b Protein, map1lc3b.L Protein

Background:

Background: Microtubule-associated proteins 1A/1B light chain 3B (MAP1LC3B) is a member of the highly conserved ATG8 protein family. ATG8 proteins are present in all known eukaryotic organisms. MAP1LC3B is one of the four genes in the MAP1LC3 subfamily (others include MAP1LC3A, MAP1LC3C, and MAP1LC3B2). It is moat abundantly expressed in heart, brain, skeletal muscle and testis. LMAP1LC3B is a subunit of neuronal microtubule and functions in formation of autophagosomal vacuoles (autophagosomes). It associated MAP1A and MAP1B proteins, which are involved in microtubule assembly and important for neurogenesis. MAP1LC3B also plays a role in autophagy, a process that involves the bulk degradation of cytoplasmic component.

Synonym: Microtubule-associated proteins 1A/1B light chain 3B, Autophagy-related protein LC3 B, Autophagy-related ubiquitin-like modifier LC3 B, MAP1 light chain 3-like protein 2, MAP1A/MAP1B light chain 3 B, MAP1A/MAP1B LC3 B, Microtubule-associated protein 1 light chain 3 beta, MAP1LC3B, MAP1ALC3

Molecular Weight: 14.8 kDa

UniProt: Q9GZQ8

Pathways: Autophagy