LSM4 Protein (His tag)
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- Target See all LSM4 Proteins
- LSM4 (LSM4 Homolog, U6 Small Nuclear RNA Associated (LSM4))
- Protein Type
- Recombinant
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Origin
- Human
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Source
- Escherichia coli (E. coli)
- Purification tag / Conjugate
- This LSM4 protein is labelled with His tag.
- Purpose
- Recombinant Human LSM4 Protein (His Tag)
- Sequence
- Met 1-Gln139
- Characteristics
- Recombinant Human U6 snRNA-Associated Sm-Like Protein LSm4 is produced by our E.coli expression system and the target gene encoding Met1-Gln139 is expressed with a 6His tag at the N-terminus.
- Purity
- > 90 % as determined by reducing SDS-PAGE.
- Endotoxin Level
- < 1.0 EU per μg as determined by the LAL method.
- Top Product
- Discover our top product LSM4 Protein
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- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Please refer to the printed manual for detailed information.
- Buffer
- Lyophilized from a 0.2 μm filtered solution of 20 mM TrisHCl, 100 mM NaCl, 1 mM DTT, pH 8.0 .
- Storage
- 4 °C,-20 °C,-80 °C
- Storage Comment
- Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
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- Target
- LSM4 (LSM4 Homolog, U6 Small Nuclear RNA Associated (LSM4))
- Alternative Name
- LSM4 (LSM4 Products)
- Synonyms
- GRP Protein, YER112W Protein, LSM4 homolog, U6 small nuclear RNA and mRNA degradation associated S homeolog Protein, LSM4 homolog, U6 small nuclear RNA and mRNA degradation associated Protein, lsm4.S Protein, LSM4 Protein, Lsm4 Protein
- Background
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Background: U6 snRNA-associated Sm-like protein LSm4 (LSM4) is a member of the snRNP Sm proteins family. Sm-like proteins contain the Sm sequence motif and are thought to form a stable heteromer present in tri-snRNP particles, which are important for pre-mRNA splicing. LSM4 forms a heteromer with a donut shape. The complexes are involved in various steps of RNA metabolism. LSM4 binds specifically to the 3-terminal U-tract of U6 snRNA. LSM4 contributes RNA protein interactions and structural changes which are essential during ribosomal subunit assembly.
Synonym: U6 snRNA-Associated Sm-Like Protein LSm4, Glycine-Rich Protein, GRP, LSM4
- Molecular Weight
- 17.5 kDa
- UniProt
- Q9Y4Z0
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