LECT1 Protein (Fc Tag)
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- Target See all LECT1 Proteins
- LECT1 (Leukocyte Cell Derived Chemotaxin 1 (LECT1))
- Protein Type
- Recombinant
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Origin
- Human
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Source
- HEK-293 Cells
- Purification tag / Conjugate
- This LECT1 protein is labelled with Fc Tag.
- Purpose
- Recombinant Human LECT1 Protein (Fc Tag)
- Sequence
- Glu215-Val333
- Characteristics
- A DNA sequence encoding the human LECT1 (NP_001011705.1) (Glu215-Val333) was expressed with the Fc region of human IgG1 at the N-terminus.
- Purity
- > (81.7+13.6) % as determined by reducing SDS-PAGE..
- Endotoxin Level
- < 1.0 EU per μg of the protein as determined by the LAL method.
- Top Product
- Discover our top product LECT1 Protein
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- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Please refer to the printed manual for detailed information.
- Buffer
- Lyophilized from sterile PBS, pH 7.4
- Storage
- 4 °C,-20 °C,-80 °C
- Storage Comment
- Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
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- Target
- LECT1 (Leukocyte Cell Derived Chemotaxin 1 (LECT1))
- Alternative Name
- LECT1 (LECT1 Products)
- Synonyms
- chm1 Protein, chm-i Protein, bricd3 Protein, MGC53801 Protein, MGC82444 Protein, chondromodulin-I Protein, Lect1 Protein, BRICD3 Protein, CHM-I Protein, CHM1 Protein, MYETS1 Protein, Bricd3 Protein, ChM-I Protein, Chm-1 Protein, chondromodulin L homeolog Protein, leukocyte cell derived chemotaxin 1 Protein, chondromodulin Protein, cnmd.L Protein, lect1 Protein, CNMD Protein, cnmd Protein, Cnmd Protein
- Background
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Background: PTGDS, also known as L-PGDS, belongs to the calycin superfamily,lipocalin family. Lipocalins share limited regions of sequence homology and a common tertiary structure architecture. They transport small hydrophobic molecules such as steroids, bilins, retinoids, and lipids. PTGDS is a glutathione-independent prostaglandin D synthase that catalyzes the conversion of PGH2 to PGD2. It is involved in smooth muscle contraction/relaxation and a variety of central nervous system functions. PTGDS may have an anti-apoptotic role in oligodendrocytes. It binds small non-substrate lipophilic molecules, including biliverdin, bilirubin, retinal, retinoic acid and thyroid hormone, and may act as a scavenger for harmful hydrophopic molecules and as a secretory retinoid and thyroid hormone transporter. It is likely to play important roles in both maturation and maintenance of the central nervous system and male reproductive system.
Synonym: BRICD3,CHM-I,CHM1,MYETS1
- Molecular Weight
- 42.1 kDa
- NCBI Accession
- NP_001011705
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