LMAN2 Protein (His tag)
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- Target See all LMAN2 Proteins
- LMAN2 (Lectin, Mannose-Binding 2 (LMAN2))
- Protein Type
- Recombinant
- Origin
- Human
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Source
- Escherichia coli (E. coli)
- Purification tag / Conjugate
- This LMAN2 protein is labelled with His tag.
- Purpose
- Recombinant Human LMAN2/VIP36 Protein (E.coli, His Tag)
- Sequence
- As p45-Arg 322
- Characteristics
- A DNA sequence encoding the human LMAN2 extracellular domain (Q12907) (As p45-Arg 322) was fused with a polyhistidine tag at the C-terminus and an initial Met at the N-terminus.
- Purity
- > 95 % as determined by reducing SDS-PAGE.
- Top Product
- Discover our top product LMAN2 Protein
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- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Please refer to the printed manual for detailed information.
- Buffer
- Lyophilized from sterile 50 mM Tris, pH 8.5
- Storage
- 4 °C,-20 °C,-80 °C
- Storage Comment
- Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
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- Target
- LMAN2 (Lectin, Mannose-Binding 2 (LMAN2))
- Alternative Name
- LMAN2/VIP36 (LMAN2 Products)
- Synonyms
- Lman2 Protein, wu:fb16f04 Protein, zgc:158761 Protein, C5orf8 Protein, GP36B Protein, VIP36 Protein, 1110003H06Rik Protein, 1300009F09Rik Protein, AA408240 Protein, AL023023 Protein, AU040819 Protein, Vip36 Protein, lectin, mannose binding 2 Protein, lectin, mannose-binding 2 Protein, LMAN2 Protein, lman2 Protein, Lman2 Protein
- Background
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Background: The L-type lectin LMAN2 (also known as VIP36) appears to be specifically required for the accumulation of GPRC5B in the Golgi complex and restriction of GPRC5B transport along the exosomal pathway. This may occur due to interference with the adaptor protein GGA1-mediated trans Golgi network-to-endosome transport of GPRC5B.A Golgi-traversing pathway for exosomal release of the cargo protein GPRC5B in which CD2AP facilitates the entry and LMAN2 impedes the exit of the flux, respectively.
Synonym: Vesicular Integral-Membrane Protein VIP36, Glycoprotein GP36b, Lectin Mannose-Binding 2, Vesicular Integral-Membrane Protein 36, VIP36, LMAN2, C5orf8
- Molecular Weight
- 33.2 kDa
- UniProt
- Q12907
- Pathways
- SARS-CoV-2 Protein Interactome
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