Lactoferrin Protein (His tag)

Catalog No. ABIN7318710

Product Details

Target: Lactoferrin (LTF) (Lactotransferrin (LTF))

Protein Type: Recombinant

Origin: Human

Source: Human Cells

Purification tag / Conjugate: This Lactoferrin protein is labelled with His tag.

Purpose: Recombinant Human Lactotransferrin/LTF Protein (His Tag)

Sequence: Gly20-Lys710

Characteristics: Recombinant Human Lactotransferrin/LTF is produced by our Mammalian expression system and the target gene encoding Gly20-Lys710 is expressed with a 6His tag at the C-terminus.

Purity: > 95 % as determined by reducing SDS-PAGE.

Endotoxin Level: < 1.0 EU per μg as determined by the LAL method.

Application Details

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Please refer to the printed manual for detailed information.

Buffer: Lyophilized from a 0.2 μm filtered solution of 20 mM PB,150 mM NaCl, pH 7.4.

Storage: 4 °C,-20 °C,-80 °C

Storage Comment: Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.

Target Details

Target: Lactoferrin (LTF) (Lactotransferrin (LTF))

Alternative Name: Lactotransferrin/LTF (LTF Products)

Synonyms: LTF Protein, GIG12 Protein, HLF2 Protein, LF Protein, Lf Protein, Csp82 Protein, MMS10R Protein, Ms10r Protein, PLF Protein, TFEW Protein, conalbumin Protein, lactotransferrin Protein, transferrin Protein, transferrin (ovotransferrin) Protein, LTF Protein, CpipJ_CPIJ000114 Protein, TF Protein, Ltf Protein

Background:

Background: Lactotransferrin is a member of the transferrin family that transfer iron to the cells and control the level of free iron in the blood and external secretions. Lactotransferrin is a secreted protein and contains two transferrin-like domains. Lactotransferrin can be cleaved into the following four chains: Kaliocin-1, Lactoferroxin-A, Lactoferroxin-B, and Lactoferroxin-C. Lactoferroxin A, Lactoferroxin B, and Lactoferroxin C have opioid antagonist activity. Lactoferroxin A shows preference for mu-receptors, while Lactoferroxin B and Lactoferroxin C have somewhat higher degrees of preference for kappa-receptors than for mu-receptors. LTF has antimicrobial activity (bacteriocide, fungicide) and is part of the innate defense, mainly at mucoses.

Synonym: Lactotransferrin, Lactoferrin, Talalactoferrin, Kaliocin-1, Lactoferroxin-A, Lactoferroxin-B, Lactoferroxin-C, LTF, LF,GIG12,HEL110,HLF2

Molecular Weight: 77.3 kDa

UniProt: P02788

Pathways: Transition Metal Ion Homeostasis