Lactoferrin Protein (His tag)
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- Target See all Lactoferrin (LTF) Proteins
- Lactoferrin (LTF) (Lactotransferrin (LTF))
- Protein Type
- Recombinant
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Origin
- Human
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Source
- Human Cells
- Purification tag / Conjugate
- This Lactoferrin protein is labelled with His tag.
- Purpose
- Recombinant Human Lactotransferrin/LTF Protein (His Tag)
- Sequence
- Gly20-Lys710
- Characteristics
- Recombinant Human Lactotransferrin/LTF is produced by our Mammalian expression system and the target gene encoding Gly20-Lys710 is expressed with a 6His tag at the C-terminus.
- Purity
- > 95 % as determined by reducing SDS-PAGE.
- Endotoxin Level
- < 1.0 EU per μg as determined by the LAL method.
- Top Product
- Discover our top product LTF Protein
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- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Please refer to the printed manual for detailed information.
- Buffer
- Lyophilized from a 0.2 μm filtered solution of 20 mM PB,150 mM NaCl, pH 7.4.
- Storage
- 4 °C,-20 °C,-80 °C
- Storage Comment
- Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
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- Target
- Lactoferrin (LTF) (Lactotransferrin (LTF))
- Alternative Name
- Lactotransferrin/LTF (LTF Products)
- Background
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Background: Lactotransferrin is a member of the transferrin family that transfer iron to the cells and control the level of free iron in the blood and external secretions. Lactotransferrin is a secreted protein and contains two transferrin-like domains. Lactotransferrin can be cleaved into the following four chains: Kaliocin-1, Lactoferroxin-A, Lactoferroxin-B, and Lactoferroxin-C. Lactoferroxin A, Lactoferroxin B, and Lactoferroxin C have opioid antagonist activity. Lactoferroxin A shows preference for mu-receptors, while Lactoferroxin B and Lactoferroxin C have somewhat higher degrees of preference for kappa-receptors than for mu-receptors. LTF has antimicrobial activity (bacteriocide, fungicide) and is part of the innate defense, mainly at mucoses.
Synonym: Lactotransferrin, Lactoferrin, Talalactoferrin, Kaliocin-1, Lactoferroxin-A, Lactoferroxin-B, Lactoferroxin-C, LTF, LF,GIG12,HEL110,HLF2
- Molecular Weight
- 77.3 kDa
- UniProt
- P02788
- Pathways
- Transition Metal Ion Homeostasis
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