KEL Protein (His tag)

Catalog No. ABIN7318702

Product Details

Target: KEL (Kell Blood Group, Metallo-Endopeptidase (KEL))

Protein Type: Recombinant

Origin: Human

Source: Human Cells

Purification tag / Conjugate: This KEL protein is labelled with His tag.

Purpose: Recombinant Human KEL/CD238 Protein (His Tag)

Sequence: Asn68-Trp732

Characteristics: Recombinant Human Kelch-like protein 41 is produced by our Mammalian expression system and the target gene encoding Asn68-Trp732 is expressed with a 6His tag at the C-terminus.

Purity: > 95 % as determined by reducing SDS-PAGE.

Endotoxin Level: < 1.0 EU per μg as determined by the LAL method.

Application Details

Restrictions: For Research Use only

Handling

Format: Frozen, Liquid

Buffer: Supplied as a 0.2 μm filtered solution of 20 mM PB,150 mM NaCl, pH 7.4.

Storage: -20 °C

Storage Comment: Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles.

Target Details

Target: KEL (Kell Blood Group, Metallo-Endopeptidase (KEL))

Alternative Name: KEL/CD238 (KEL Products)

Synonyms: CD238 Protein, Ece3 Protein, ECE3 Protein, Kell blood group Protein, Kell blood group, metallo-endopeptidase Protein, Kel Protein, KEL Protein

Background:

Background: Kell blood group glycoprotein (KEL) is a single-pass type II membrane protein which belongs to the peptidase M13 family. It is expressed in Expressed at high levels in erythrocytes and testis, and, at lower levels, in skeletal muscle, tonsils, lymph node, spleen and appendix. KEL has been shown zinc endopeptidase with endothelin-3-converting enzyme activity. It cleaves EDN1, EDN2 and EDN3, with a marked preference for EDN3. It links via a single disulfide bond to the XK membrane protein that carries the Kx antigen.

Synonym: Kell blood group glycoprotein, CD238, KEL

Molecular Weight: 78.4 kDa

UniProt: P23276