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Kallikrein 11 Protein (KLK11) (His tag)

KLK11 Origin: Human Host: Human Cells Recombinant > 95 % as determined by reducing SDS-PAGE.
Catalog No. ABIN7319354
  • Target See all Kallikrein 11 (KLK11) Proteins
    Kallikrein 11 (KLK11)
    Protein Type
    Recombinant
    Origin
    • 8
    • 1
    • 1
    • 1
    Human
    Source
    • 4
    • 4
    • 1
    • 1
    • 1
    Human Cells
    Purification tag / Conjugate
    This Kallikrein 11 protein is labelled with His tag.
    Purpose
    Recombinant Human Kallikrein 11/KLK11 Protein (His Tag)
    Sequence
    Glu19-Asn250
    Characteristics
    Recombinant Human Kallikrein 11 is produced by our Mammalian expression system and the target gene encoding Glu19-Asn250 is expressed with a 6His tag at the C-terminus.
    Purity
    > 95 % as determined by reducing SDS-PAGE.
    Endotoxin Level
    < 1.0 EU per μg as determined by the LAL method.
    Top Product
    Discover our top product KLK11 Protein
  • Restrictions
    For Research Use only
  • Format
    Frozen, Liquid
    Buffer
    Supplied as a 0.2 μm filtered solution of 20 mM TrisHCl, 150 mM NaCl, 2 mM CaCl2, pH 8.0.
    Storage
    -20 °C
    Storage Comment
    Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles.
  • Target
    Kallikrein 11 (KLK11)
    Alternative Name
    Kallikrein 11/KLK11 (KLK11 Products)
    Synonyms
    KLK11 Protein, 2310015I08Rik Protein, Prss20 Protein, TLSP Protein, PRSS20 Protein, kallikrein related peptidase 11 Protein, kallikrein related-peptidase 11 Protein, kallikrein-related peptidase 11 Protein, KLK11 Protein, Klk11 Protein
    Background

    Background: Human Kallikrein 11 (KLK11) is a member of tissue kallikrein family which are extracellular serine proteases consisting of 15 members. Two isoforms of KLK11 are differentially expressed. Isoform 1 is predominantly expressed in brain and isoform 2 is preferentially expressed in prostate. Isoform 1 consists of a signal peptide,a short pro peptide and the mature chain.Isoform 2 contains an extra 32 amino acid N terminal to full-length isoform 1.KLK11 is a novel marker for ovarian and prostate cancer carcinomas. KLK11 can be activated by thermolysin and is active against a thioester substrate.

    Synonym: Kallikrein-11, hK11, Hippostasin, Serine Protease 20, Trypsin-Like Protease, KLK11, PRSS20, TLSP

    Molecular Weight
    26.3 kDa
    NCBI Accession
    NP_006844
    Pathways
    Complement System
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