Kallikrein 10 Protein (KLK10) (His tag)

Catalog No. ABIN7318696

Product Details

Target: Kallikrein 10 (KLK10)

Protein Type: Recombinant

Origin: Human

Source: Human Cells

Purification tag / Conjugate: This Kallikrein 10 protein is labelled with His tag.

Purpose: Recombinant Human Kallikrein 10/KLK10 Protein (His Tag)

Sequence: Ala31-Asn276

Characteristics: Recombinant Human Kallikrein 10 is produced by our Mammalian expression system and the target gene encoding Ala31-Asn276 is expressed with a 6His tag at the C-terminus.

Purity: > 95 % as determined by reducing SDS-PAGE.

Endotoxin Level: < 1.0 EU per μg as determined by the LAL method.

Application Details

Restrictions: For Research Use only

Handling

Format: Frozen, Liquid

Buffer: Supplied as a 0.2 μm filtered solution of 20 mM TrisHCl, 150 mM NaCl, pH 8.0.

Storage: -20 °C

Storage Comment: Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles.

Target Details

Target: Kallikrein 10 (KLK10)

Alternative Name: Kallikrein 10/KLK10 (KLK10 Products)

Synonyms: KLK10 Protein, 2300002A13Rik Protein, NES1 Protein, PRSSL1 Protein, kallikrein related peptidase 10 Protein, kallikrein related-peptidase 10 Protein, kallikrein-related peptidase 10 Protein, KLK10 Protein, Klk10 Protein

Background:

Background: Kallikreins are a subgroup of Serine Proteases having diverse physiological functions. Growing evidence suggests that many Kallikreins are implicated in carcinogenesis and some have potential as novel cancer and other disease biomarkers. This gene is one of the fifteen Kallikrein subfamily members located in a cluster on chromosome 19. Its encoded protein is secreted and may play a role in suppression of tumorigenesis in breast and prostate cancers. Alternate splicing of this gene results in multiple transcript variants encoding the same protein.

Synonym: Kallikrein-10, Normal Epithelial Cell-Specific 1, Protease Serine-Like 1, KLK10, NES1, PRSSL1

Molecular Weight: 28.0 kDa

UniProt: O43240

Pathways: Complement System