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IL-5 Protein (His tag)

IL5 Origin: Mouse Host: Human Cells Recombinant >95 % as determined by reducing SDS-PAGE.
Catalog No. ABIN7320883
  • Target See all IL-5 (IL5) Proteins
    IL-5 (IL5) (Interleukin 5 (IL5))
    Protein Type
    Recombinant
    Origin
    • 16
    • 11
    • 7
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Mouse
    Source
    • 26
    • 14
    • 9
    • 3
    • 2
    • 2
    • 1
    • 1
    Human Cells
    Purification tag / Conjugate
    This IL-5 protein is labelled with His tag.
    Purpose
    Recombinant Mouse Interleukin-5/IL-5 (C-6His)
    Sequence
    Met21-Gly133
    Characteristics
    Recombinant Mouse Interleukin-5 is produced by our Mammalian expression system and the target gene encoding Met21-Gly133 is expressed with a 6His tag at the C-terminus.
    Purity
    >95 % as determined by reducing SDS-PAGE.
    Endotoxin Level
    < 1.0 EU per μg as determined by the LAL method.
    Top Product
    Discover our top product IL5 Protein
  • Restrictions
    For Research Use only
  • Format
    Lyophilized
    Reconstitution
    Please refer to the printed manual for detailed information.
    Buffer
    Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4.
    Storage
    4 °C,-20 °C,-80 °C
    Storage Comment
    Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
  • Target
    IL-5 (IL5) (Interleukin 5 (IL5))
    Alternative Name
    Interleukin-5/IL-5 (IL5 Products)
    Synonyms
    EDF Protein, IL-5 Protein, TRF Protein, Il-5 Protein, IL5 Protein, interleukin 5 Protein, IL5 Protein, Il5 Protein
    Background

    Background: IL-5 is expressed in eosinophils, NK cells, TC2 CD8+ T cells, mast cells, CD45+ CD4+ T cells, gamma delta T cells and IL-1 beta activated endothelial cells. IL-5 acts as a growth and differentiation factor for both B cells and eosinophils. Relative to B cells, IL-5 appears to induce the differentiation of activated conventional B-2 cells into Ig-secreting cells. In addition, it induces the growth of B-1 progenitors as well as IgM production by B-1 cells.IL-5 appears to perform a number of functions on eosinophils. These include the down modulation of Mac-1,the upregulation of receptors for IgA and IgG,the stimulation of lipid mediator (leukotriene C4 and PAF) secretion and the induction of granule release.IL-5 also promotes the growth and differentiation of eosinophils.

    Synonym: Prolactin, PRL

    Molecular Weight
    13.9 kDa
    UniProt
    P04401
    Pathways
    JAK-STAT Signaling, Positive Regulation of Peptide Hormone Secretion, Production of Molecular Mediator of Immune Response, Feeding Behaviour
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