IL2RG Protein (Fc Tag)

Catalog No. ABIN7320815

Product Details

Target: IL2RG (Interleukin 2 Receptor, gamma (IL2RG))

Protein Type: Recombinant

Origin: Mouse

Source: Human Cells

Purification tag / Conjugate: This IL2RG protein is labelled with Fc Tag.

Purpose: Recombinant Mouse IL-2RG/CD132 Protein (Fc Tag)

Sequence: Ser25-Ala263

Characteristics: Recombinant Mouse Interleukin-2 Receptor Subunit Gamma is produced by our Mammalian expression system and the target gene encoding Ser25-Ala263 is expressed with a Fc tag at the C-terminus.

Purity: > 95 % as determined by reducing SDS-PAGE.

Endotoxin Level: < 1.0 EU per μg as determined by the LAL method.

Application Details

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Please refer to the printed manual for detailed information.

Buffer: Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4.

Storage: 4 °C,-20 °C,-80 °C

Storage Comment: Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.

Target Details

Target: IL2RG (Interleukin 2 Receptor, gamma (IL2RG))

Alternative Name: IL-2RG/CD132 (IL2RG Products)

Synonyms: Ab2-183 Protein, Cd132 Protein, CD132 Protein, CIDX Protein, IL-2RG Protein, IMD4 Protein, P64 Protein, SCIDX Protein, SCIDX1 Protein, [g]c Protein, gamma(c) Protein, gc Protein, interleukin 2 receptor subunit gamma Protein, interleukin 2 receptor subunit gamma L homeolog Protein, interleukin 2 receptor, gamma chain Protein, IL2RG Protein, il2rg.L Protein, Il2rg Protein

Background:

Background: The Interleukin-2 receptor gamma chain (IL-2 Rγ, CD132) of the high affinity functional mouse IL-2 receptor complex is a member the hematopoietin receptor family. It is expressed on most lymphocyte (white blood cell) populations, and its gene is found on the X-chromosome of mammals. Common IL2 receptor-γ Chain is required for IL-2 receptor signaling. Besides IL-2, the Common IL2 receptor-γ chain has been shown to be a component of the functional receptor complexes for IL-4, IL-7, IL-9 and IL-15. It is a component of multiple cytokine receptors that are essential for lymphocyte development and function. Common IL2 receptor-γ Chain is also designated the common gamma chain.

Synonym: Interleukin 2 receptor, gamma chain, isoform CRA_b, Il2rg, CIDX, IL-2 Rγ

Molecular Weight: 55.1 kDa

UniProt: Q3UPA9

Pathways: JAK-STAT Signaling, Growth Factor Binding