IL17F Protein (His tag)
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- Target See all IL17F Proteins
- IL17F (Interleukin 17F (IL17F))
- Protein Type
- Recombinant
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Origin
- Mouse
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Source
- Human Cells
- Purification tag / Conjugate
- This IL17F protein is labelled with His tag.
- Purpose
- Recombinant Mouse Interleukin-17F/IL-17F Protein (His Tag)
- Sequence
- Arg29-Ala161
- Characteristics
- Recombinant Mouse Interleukin-17F is produced by our Mammalian expression system and the target gene encoding Arg29-Ala161 is expressed with a 6His tag at the C-terminus.
- Purity
- > 95 % as determined by SDS-PAGE
- Endotoxin Level
- < 1.0 EU per μg as determined by the LAL method.
- Top Product
- Discover our top product IL17F Protein
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- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Please refer to the printed manual for detailed information.
- Buffer
- Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4.
- Storage
- 4 °C,-20 °C,-80 °C
- Storage Comment
- Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
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- Target
- IL17F (Interleukin 17F (IL17F))
- Alternative Name
- Interleukin-17F/IL-17F (IL17F Products)
- Synonyms
- CANDF6 Protein, IL-17F Protein, ML-1 Protein, ML1 Protein, C87042 Protein, IL17F Protein, interleukin 17F Protein, IL17F Protein, Il17f Protein
- Background
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Background: Interleukin-17F (IL-17F) exists in a disulfide-linked heterodimer that belongs to the IL-17 family. IL-17F is expressed in activated, but not resting, CD4+ T-cells and activated monocytes. Mouse and human IL-17F share 55 % sequence identity.IL-17F has been shown to stimulate the production of several other cytokines, including IL-6, IL-8, and granulocyte colony-stimulating factor. IL-17F can regulate cartilage matrix turnover and stimulates PBMC and T-cell proliferation. IL-17F is also found to inhibit the angiogenesis of endothelial cells and induce endothelial cells to produce IL2, TGFB1/TGFB, and monocyte chemoattractant protein-1. Defects in IL-17F are the cause of familial candidiasis type 6 (CANDF6).
Synonym: Interleukin-17F, IL-17F, Cytokine ML-1, Interleukin-24, IL-24, IL17F, IL24
- Molecular Weight
- 15.9 kDa
- UniProt
- Q7TNI7
- Pathways
- Cellular Response to Molecule of Bacterial Origin, Positive Regulation of Endopeptidase Activity
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