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IL-11 Protein (Fc Tag)

IL11 Origin: Mouse Host: Human Cells Recombinant > 95 % as determined by reducing SDS-PAGE.
Catalog No. ABIN7320821
  • Target See all IL-11 (IL11) Proteins
    IL-11 (IL11) (Interleukin 11 (IL11))
    Protein Type
    Recombinant
    Origin
    • 15
    • 7
    • 2
    • 2
    Mouse
    Source
    • 10
    • 5
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    Human Cells
    Purification tag / Conjugate
    This IL-11 protein is labelled with Fc Tag.
    Purpose
    Recombinant Mouse Interleukin-11/IL-11 Protein (Fc Tag)
    Sequence
    Pro22-Leu199
    Characteristics
    Recombinant Mouse Interleukin-11 is produced by our Mammalian expression system and the target gene encoding Pro22-Leu199 is expressed with a Fc tag at the C-terminus.
    Purity
    > 95 % as determined by reducing SDS-PAGE.
    Endotoxin Level
    < 1.0 EU per μg as determined by the LAL method.
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    Discover our top product IL11 Protein
  • Restrictions
    For Research Use only
  • Format
    Lyophilized
    Reconstitution
    Please refer to the printed manual for detailed information.
    Buffer
    Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4.
    Storage
    4 °C,-20 °C,-80 °C
    Storage Comment
    Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
  • Target
    IL-11 (IL11) (Interleukin 11 (IL11))
    Alternative Name
    Interleukin-11/IL-11 (IL11 Products)
    Synonyms
    IL11 Protein, AGIF Protein, IL-11 Protein, Il-11 Protein, interleukin 11 Protein, IL11 Protein, Il11 Protein
    Background

    Background: Interleukin-11(IL-11) is a secreted protein and belongs to the IL-6 superfamily. IL-11 has been demonstrated to improve platelet recovery after chemotherapy-induced thrombocytopenia, induceacute phase proteins, modulate antigen-antibody responses, participate in the regulation of bone cellproliferation and differentiation and could be use as a therapeutic for osteoporosis. IL-11 stimulates the growth of certain lymphocytes and, in the murine model, stimulates an increase in the cortical thickness and strength of long bones. In addition to having lymphopoietic/hematopoietic and osteotrophic properties, it has functions in many other tissues, including the brain, gut, testis and bone.

    Synonym: Interleukin-11,Il11,IL-11

    Molecular Weight
    46.3 kDa
    UniProt
    P47873
    Pathways
    JAK-STAT Signaling, Negative Regulation of Hormone Secretion
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