IL1RL1 Protein
-
- Target See all IL1RL1 Proteins
- IL1RL1 (Interleukin 1 Receptor-Like 1 (IL1RL1))
- Protein Type
- Recombinant
-
Origin
- Human
-
Source
- HEK-293 Cells
- Purpose
- Recombinant Human IL1RL1/ST2 Protein
- Sequence
- Met 1-Phe 328
- Characteristics
- The secreted isoform of human IL1RL1 (NP_003847.2) (Met 1-Phe 328) with five amino acids (DDDDK) at the C-terminus was expressed and purified.
- Purity
- > 95 % as determined by reducing SDS-PAGE.
- Endotoxin Level
- < 1.0 EU per μg as determined by the LAL method.
- Top Product
- Discover our top product IL1RL1 Protein
-
Interleukin 1 Receptor-Like 1 (IL1RL1) (AA 19-328) protein (His tag)
IL1RL1 Origin: Human Host: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
Interleukin 1 Receptor-Like 1 (IL1RL1) (AA 19-328) (Active) protein (His tag)IL1RL1 Origin: Human Host: HEK-293 Cells Recombinant >90 % as determined by SDS-PAGE. Active
Interleukin 1 Receptor-Like 1 (IL1RL1) protein (His tag)IL1RL1 Origin: Mouse Host: Human Cells Recombinant > 95 % as determined by SDS-PAGE
Interleukin 1 Receptor-Like 1 (IL1RL1) (AA 19-328) protein (His tag)IL1RL1 Origin: Human Host: Baculovirus infected Insect Cells Recombinant > 95 % by SDS - PAGE SDS
Interleukin 1 Receptor-Like 1 (IL1RL1) (AA 1-328), (Isoform 2) (Active) protein (Fc Tag)IL1RL1 Origin: Human Host: HEK-293 Cells Recombinant >90 % (SDS-PAGE) SDS Active
Interleukin 1 Receptor-Like 1 (IL1RL1) (AA 19-323) (Active) protein (Fc Tag)IL1RL1 Origin: Human Host: HEK-293 Cells Recombinant >95 % as determined by SDS-PAGE. Active
-
- Restrictions
- For Research Use only
-
- Format
- Lyophilized
- Reconstitution
- Please refer to the printed manual for detailed information.
- Buffer
- Lyophilized from sterile 50 mM Tris, 100 mM NaCl, pH 8.0
- Storage
- 4 °C,-20 °C,-80 °C
- Storage Comment
- Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
-
- Target
- IL1RL1 (Interleukin 1 Receptor-Like 1 (IL1RL1))
- Alternative Name
- IL1RL1/ST2 (IL1RL1 Products)
- Synonyms
- DER4 Protein, Fit-1 Protein, Ly84 Protein, ST2L Protein, St2 Protein, St2-rs1 Protein, T1 Protein, T1/ST2 Protein, FIT-1 Protein, IL33R Protein, ST2 Protein, ST2V Protein, FIT1 Protein, interleukin 1 receptor-like 1 Protein, interleukin 1 receptor like 1 Protein, Il1rl1 Protein, IL1RL1 Protein
- Background
-
Background: IL-1 receptor–like 1 (IL1RL1) is a membrane receptor involved in TH2 inflammatory responses and eosinophilia. It has previously been described that levels of the interlukin-1 like 1 (IL1RL1) protein can be used to diagnose cardiovascular disease and determine the prognosis for a patient with cardiovascular disease. The ligand for IL1RL1 has been described, and named IL-33. Mutants in IL1RL1 have been associated with blood eosinophil counts in a genome-wide association study and with asthma in family-based and case-control studies. As an important mediator involved in many immune and inflammatory responses, this cytokine has been implicated as a regulator of both the development and effector phases of type 2 helper T cell responses, and as a negative feedback modulator of macrophage pro-inflammatory function. IL33 is a specific ligand of ST2L and induces production of Th2 cytokines.
Synonym: DER4;FIT-1;IL1RL1;IL33R;IL-1 R4;ST2;ST2L;ST2V;T1
- Molecular Weight
- 35.6 kDa
- NCBI Accession
- NP_003847
-
