IFNA4 Protein (His tag)
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- Target See all IFNA4 (IFNa4) Proteins
- IFNA4 (IFNa4) (Interferon, alpha 4 (IFNa4))
- Protein Type
- Recombinant
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Origin
- Human
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Source
- Human Cells
- Purification tag / Conjugate
- This IFNA4 protein is labelled with His tag.
- Purpose
- Recombinant Human IFNA4 Protein (His Tag)
- Sequence
- Cys24-Asp189
- Characteristics
- Recombinant Human Interferon alpha-4 is produced by our Mammalian expression system and the target gene encoding Cys24-Asp189 is expressed with a 6His tag at the C-terminus.
- Purity
- > 95 % as determined by reducing SDS-PAGE.
- Endotoxin Level
- < 1.0 EU per μg as determined by the LAL method.
- Top Product
- Discover our top product IFNa4 Protein
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- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Please refer to the printed manual for detailed information.
- Buffer
- Lyophilized from a 0.2 μm filtered solution of 20 mM PB,150 mM NaCl, pH 7.2.
- Storage
- 4 °C,-20 °C,-80 °C
- Storage Comment
- Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
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- Target
- IFNA4 (IFNa4) (Interferon, alpha 4 (IFNa4))
- Alternative Name
- IFNA4 (IFNa4 Products)
- Synonyms
- IFN-alpha4a Protein, INFA4 Protein, Ifa4 Protein, interferon alpha 4 Protein, interferon, alpha 4 Protein, interferon-alpha-4 Protein, IFNA4 Protein, Ifna4 Protein, LOC100052921 Protein
- Background
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Background: Interferon stimulates the production of two enzymes: a protein kinase and an oligoadenylate synthetase. They allow for communication between cells to trigger the protective defenses of the immune system that eradicate pathogens or tumors. They are typically divided among three IFN classes: Type I, Type II and Type III. IFNA4 is a secreted protein and produced by macrophages. Two variants of IFNA4 (IFNA4a and IFNA4b) are known, which differ from each other by changes in their coding regions at nucleotide positions 220 and 410 .
Synonym: Interferon alpha-4, Interferon alpha-4B, Interferon alpha-76,Interferon alpha-M1,IFNA4
- Molecular Weight
- 20.4 kDa
- UniProt
- P05014
- Pathways
- JAK-STAT Signaling, Hepatitis C
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