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Interferon zeta Protein (IFNZ) (His tag)

IFNZ Origin: Mouse Host: Human Cells Recombinant > 95 % as determined by SDS-PAGE
Catalog No. ABIN7320569
  • Target See all Interferon zeta (IFNZ) products
    Interferon zeta (IFNZ)
    Protein Type
    Recombinant
    Origin
    Mouse
    Source
    • 1
    Human Cells
    Purification tag / Conjugate
    This Interferon zeta protein is labelled with His tag.
    Purpose
    Recombinant Mouse IFN-zeta/Limitin Protein (His Tag)
    Sequence
    Leu22-Arg182
    Characteristics
    Recombinant Mouse Limitin is produced by our Mammalian expression system and the target gene encoding Leu22-Arg182 is expressed with a 6His tag at the C-terminus.
    Purity
    > 95 % as determined by SDS-PAGE
    Endotoxin Level
    < 1.0 EU per μg as determined by the LAL method.
  • Restrictions
    For Research Use only
  • Format
    Lyophilized
    Reconstitution
    Please refer to the printed manual for detailed information.
    Buffer
    Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4.
    Storage
    4 °C,-20 °C,-80 °C
    Storage Comment
    Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
  • Target
    Interferon zeta (IFNZ)
    Alternative Name
    IFN-zeta/Limitin (IFNZ Products)
    Synonyms
    6030405N23Rik Protein, BGIF Protein, Lmtn Protein, interferon zeta Protein, Ifnz Protein
    Background

    Background: Limitin, also called IFN-ζ, is a secreted interferon (IFN)-like glycoprotein. Limitin has approximately 30 % sequence homology with IFN-α, IFN-β, and IFN-ω and binds to the IFN-α/β receptors. Like IFN-α and IFN-β, limitin has antiproliferative, immunomodulatory, and antiviral properties, it is unique in lacking influence on myeloid and erythroid progenitors. Similar dose requirement between limitin and IFN-α was observed for the enhancement of cytotoxic T lymphocyte activity, the augmentation of MHC class I expression, and the growth inhibition of a myelomonocytic leukemia cell line.

    Synonym: Limitin, IFN-z, BGIF, Ifnz, interferon zeta, Lmtn, IFN-zeta

    Molecular Weight
    19.5 kDa
    UniProt
    Q9R1T0
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