ICAM2 Protein (Fc Tag)
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- Target See all ICAM2 Proteins
- ICAM2 (Intercellular Adhesion Molecule 2 (ICAM2))
- Protein Type
- Recombinant
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Origin
- Mouse
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Source
- Human Cells
- Purification tag / Conjugate
- This ICAM2 protein is labelled with Fc Tag.
- Purpose
- Recombinant Mouse ICAM-2/CD102 Protein (Fc Tag)
- Sequence
- Lys23-Gln222
- Characteristics
- Recombinant Mouse Intercellular adhesion molecule 2 is produced by our Mammalian expression system and the target gene encoding Lys23-Gln222 is expressed with a Fc tag at the C-terminus.
- Purity
- > 95 % as determined by SDS-PAGE
- Endotoxin Level
- < 1.0 EU per μg as determined by the LAL method.
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- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Please refer to the printed manual for detailed information.
- Buffer
- Lyophilized from a 0.2 μm filtered solution of 20 mM Tris,150 mM NaCl, pH 8.0.
- Storage
- 4 °C,-20 °C,-80 °C
- Storage Comment
- Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
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- Target
- ICAM2 (Intercellular Adhesion Molecule 2 (ICAM2))
- Alternative Name
- ICAM-2/CD102 (ICAM2 Products)
- Synonyms
- ICAM2 Protein, CD102 Protein, Icam-2 Protein, Ly-60 Protein, intercellular adhesion molecule 2 Protein, LOC506088 Protein, ICAM2 Protein, LOC616254 Protein, LOC100140873 Protein, Icam2 Protein
- Background
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Background: ICAM-2 is a 55-65 kD transmembrane glycoprotein possessing 2 extracellular Ig domains, a single transmembrane domain, and a short 26-amino acid cytoplasmic domain. ICAM-2 is expressed on most leukocytes, and is strongly expressed on vascular endothelial cells. Interactions of ICAM-2 and the integrin receptors mediate cell adhesion in a wide range of lymphocyte, monocyte, natural killer cell, and granulocytewith other cells, and play important roles in many adhesion-dependent immune and inflammation responses, such as T cell aggregation, NK-cell cytotoxicity and migration, lymphocyte recirculation, etc. Serum levels of ICAM-2 correlated significantly with the inflammatory and course sequences of trichinosis in mice and had a similar relation with blood eosinophilia. So, estimation of ICAM-2 serum levels may prove useful in diagnosis of trichinosis recent infections, and in monitoring the prognosis and response to treatment.
Synonym: Intercellular adhesion molecule 2, Icam2, ICAM-2, Lymphocyte function-associated AG-1 counter-receptor, CD102, Icam-2, CD102 antigen,Ly-60
- Molecular Weight
- 49.7 kDa
- NCBI Accession
- NP_034624
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