ITIH3 Protein (His tag)
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- Target See all ITIH3 Proteins
- ITIH3 (Inter alpha Globulin Inhibitor H3 (ITIH3))
- Protein Type
- Recombinant
- Origin
- Human
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Source
- Human Cells
- Purification tag / Conjugate
- This ITIH3 protein is labelled with His tag.
- Purpose
- Recombinant Human ITIH3 Protein (His Tag)
- Sequence
- Leu35-Asp651
- Characteristics
- Recombinant Human Inter-alpha-trypsin inhibitor heavy chain H3 is produced by our Mammalian expression system and the target gene encoding Leu35-Asp651 is expressed with a 6His tag at the C-terminus.
- Purity
- > 95 % as determined by reducing SDS-PAGE.
- Endotoxin Level
- < 1.0 EU per μg as determined by the LAL method.
- Top Product
- Discover our top product ITIH3 Protein
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- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Please refer to the printed manual for detailed information.
- Buffer
- Lyophilized from a 0.2 μm filtered solution of 20 mM PB,150 mM NaCl, pH 7.4.
- Storage
- 4 °C,-20 °C,-80 °C
- Storage Comment
- Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
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- Target
- ITIH3 (Inter alpha Globulin Inhibitor H3 (ITIH3))
- Alternative Name
- ITIH3 (ITIH3 Products)
- Synonyms
- AW108094 Protein, Intin3 Protein, Itih-3 Protein, PAIHC3 Protein, H3P Protein, ITI-HC3 Protein, Itih3 Protein, inter-alpha trypsin inhibitor, heavy chain 3 Protein, inter-alpha-trypsin inhibitor heavy chain 3 Protein, Itih3 Protein, ITIH3 Protein
- Background
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Background: ITIH3, which is short for Inter-alpha-trypsin inhibitor heavy chain H3, is a 890 aa. protein. It is secreted expression, and belongs to the ITIH family. I-alpha-I plasma protease inhibitors are assembled from one or two heavy chains (H1, H2 or H3) and one light chain, bikunin. Inter-alpha-inhibitor (I-alpha-I) is composed of H1, H2 and bikunin, inter-alpha-like inhibitor (I-alpha-LI) of H2 and bikunin, and pre-alpha-inhibitor (P-alpha-I) of H3 and bikunin. ITTH3 may act as a carrier of hyaluronan in serum or as a binding protein between hyaluronan and other matrix protein, including those on cell surfaces in tissues to regulate the localization, synthesis and degradation of hyaluronan which are essential to cells undergoing biological processes.
Synonym: Inter-alpha-trypsin inhibitor heavy chain H3,ITI heavy chain H3,ITI-HC3,Inter-alpha-inhibitor heavy chain 3,Serum-derived hyaluronan-associated protein,SHAP
- Molecular Weight
- 70.4 kDa
- UniProt
- Q06033
- Pathways
- Glycosaminoglycan Metabolic Process
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