ITPA Protein (His tag)
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- Target See all ITPA Proteins
- ITPA (Inosine Triphosphatase (ITPA))
- Protein Type
- Recombinant
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Origin
- Human
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Source
- Escherichia coli (E. coli)
- Purification tag / Conjugate
- This ITPA protein is labelled with His tag.
- Purpose
- Recombinant Human ITPase/ITPA Protein (His Tag)
- Sequence
- Ala2-Ala194
- Characteristics
- Recombinant Human Inosine Triphosphate Pyrophosphatase is produced by our E.coli expression system and the target gene encoding Ala2-Ala194 is expressed with a 6His tag at the C-terminus.
- Purity
- > 95 % as determined by reducing SDS-PAGE.
- Endotoxin Level
- < 1.0 EU per μg as determined by the LAL method.
- Top Product
- Discover our top product ITPA Protein
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Inosine Triphosphatase (ITPA) (AA 1-194) protein (GST tag)
ITPA Origin: Human Host: Wheat germ Recombinant ELISA, WB, AP, AA
Inosine Triphosphatase (ITPA) (AA 1-194) protein (His tag)ITPA Origin: Human Host: Escherichia coli (E. coli) Recombinant Greater than 95 % as determined by SDS-PAGE ELISA, WB
Inosine Triphosphatase (ITPA) (AA 3-180) protein (S tag,His tag)ITPA Origin: Human Host: Escherichia coli (E. coli) Recombinant ≥ 92 % ELISA, WB, SDS, IP
Inosine Triphosphatase (ITPA) (AA 2-198) protein (GST tag,His tag)ITPA Origin: Mouse Host: Escherichia coli (E. coli) Recombinant ≥ 95 % ELISA, WB, SDS, IP
Inosine Triphosphatase (ITPA) (Transcript Variant 1) protein (His tag)ITPA Origin: Human Host: Escherichia coli (E. coli) Recombinant > 95 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
Inosine Triphosphatase (ITPA) (Transcript Variant 1) protein (Myc-DYKDDDDK Tag)ITPA Origin: Human Host: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
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- Restrictions
- For Research Use only
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- Format
- Frozen, Liquid
- Buffer
- Supplied as a 0.2 μm filtered solution of 20 mM TrisHCl, pH 8.0.
- Storage
- -20 °C
- Storage Comment
- Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles.
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- Target
- ITPA (Inosine Triphosphatase (ITPA))
- Alternative Name
- ITPase/ITPA (ITPA Products)
- Background
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Background: Inosine Triphosphate Pyrophosphatase (ITPase) is a cytoplasmic enzyme that belongs to the HAM1 NTPase family. ITPase hydrolyzes the non-canonical purine nucleotides inosine triphosphate (ITP) and deoxyinosine triphosphate (dITP) to the monophosphate nucleotide (IMP) and diphosphate. The ITPase enzyme acts as a homodimer and does not distinguish between the deoxy- and ribose forms. ITPase probably excludes non-canonical purines from RNA and DNA precursor pools, thus preventing their incorporation into RNA and DNA and avoiding chromosomal lesions. Defects in ITPase is thought to be inherited and is characterized by an over-accumulation of ITP in erythocytes, leukocytes and fibroblasts.
Synonym: Inosine Triphosphate Pyrophosphatase, ITPase, Inosine Triphosphatase, Non-Canonical Purine NTP Pyrophosphatase, Non-Standard Purine NTP Pyrophosphatase, Nucleoside-Triphosphate Diphosphatase, Nucleoside-Triphosphate Pyrophosphatase, NTPase, Putative Oncogene Protein hlc14-06-p, ITPA, C20orf37
- Molecular Weight
- 22.5 kDa
- UniProt
- Q9BY32
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