HMBS Protein (His tag)
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- Target See all HMBS Proteins
- HMBS (Hydroxymethylbilane Synthase (HMBS))
- Protein Type
- Recombinant
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Origin
- Human
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Source
- Human Cells
- Purification tag / Conjugate
- This HMBS protein is labelled with His tag.
- Purpose
- Recombinant Human HMBS Protein (His Tag)
- Sequence
- Ser2-His361
- Characteristics
- Recombinant Human Porphobilinogen Deaminase is produced by our Mammalian expression system and the target gene encoding Ser2-His361 is expressed with a 6His tag at the C-terminus.
- Purity
- > 95 % as determined by reducing SDS-PAGE.
- Endotoxin Level
- < 1.0 EU per μg as determined by the LAL method.
- Top Product
- Discover our top product HMBS Protein
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Hydroxymethylbilane Synthase (HMBS) (AA 1-361) protein (His tag)
HMBS Origin: Human Host: Escherichia coli (E. coli) Recombinant Greater than 95 % as determined by SDS-PAGE WB, ELISA
Hydroxymethylbilane Synthase (HMBS) (AA 1-361) protein (GST tag)HMBS Origin: Human Host: Wheat germ Recombinant WB, ELISA, AP, AA
Hydroxymethylbilane Synthase (HMBS) (Transcript Variant 2) protein (Myc-DYKDDDDK Tag)HMBS Origin: Human Host: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
Hydroxymethylbilane Synthase (HMBS) (Transcript Variant 1) protein (Myc-DYKDDDDK Tag)HMBS Origin: Human Host: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
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- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Please refer to the printed manual for detailed information.
- Buffer
- Lyophilized from a 0.2 μm filtered solution of 20 mM PB,150 mM NaCl, pH 7.4.
- Storage
- 4 °C,-20 °C,-80 °C
- Storage Comment
- Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
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- Target
- HMBS (Hydroxymethylbilane Synthase (HMBS))
- Alternative Name
- HMBS (HMBS Products)
- Synonyms
- PBG-D Protein, PBGD Protein, PORC Protein, UPS Protein, URO-S Protein, hemC Protein, pbg-d Protein, pbgd Protein, ups Protein, SPAC806.01 Protein, DDBDRAFT_0186148 Protein, DDBDRAFT_0231417 Protein, DDB_0186148 Protein, DDB_0231417 Protein, Hmbs Protein, NV50236 Protein, T25658 Protein, Ups Protein, Uros1 Protein, hmbs Protein, zgc:64128 Protein, hmbsl Protein, id:ibd5004 Protein, im:7140060 Protein, zgc:110690 Protein, hydroxymethylbilane synthase Protein, hydroxymethylbilane synthase S homeolog Protein, hydroxymethylbilane synthase L homeolog Protein, hydroxymethylbilane synthase (predicted) Protein, Hydroxymethylbilane synthase Protein, hydroxymethylbilane synthase a Protein, hydroxymethylbilane synthase, b Protein, HMBS Protein, Hmbs Protein, hmbs Protein, hmbs.2.S Protein, hmbs.L Protein, CNC02250 Protein, hem3 Protein, hemC Protein, Trad_0335 Protein, Plabr_2100 Protein, Sgly_3113 Protein, SMLT_RS19660 Protein, PMI_RS16580 Protein, hmbsa Protein, hmbsb Protein
- Background
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Background: Porphobilinogen Deaminase (HMBS) is a member of the HMBS family. PBGD is the third enzyme of the heme biosynthetic pathway and catalyzes the head to tail condensation of four porphobilinogen molecules into the linear hydroxymethylbilane. HMBS is involved in the production of heme, which is important for all of the body's organs, although it is most abundant in the blood, bone marrow, and liver. In addition, Heme is an essential component of iron-containing proteins called hemoproteins, including hemoglobin. Defects in PBGD are the cause of acute intermittent porphyria.
Synonym: Porphobilinogen Deaminase, PBG-D, Hydroxymethylbilane Synthase, HMBS, Pre-Uroporphyrinogen Synthase, HMBS, PBGD, UPS
- Molecular Weight
- 40.5 kDa
- UniProt
- P08397
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