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HYAL1 Protein (His tag)

HYAL1 Origin: Human Host: Human Cells Recombinant > 95 % as determined by reducing SDS-PAGE.
Catalog No. ABIN7318588
  • Target See all HYAL1 Proteins
    HYAL1 (Hyaluronidase-1 (HYAL1))
    Protein Type
    Recombinant
    Origin
    • 8
    • 2
    • 1
    • 1
    • 1
    Human
    Source
    • 4
    • 3
    • 3
    • 2
    • 1
    Human Cells
    Purification tag / Conjugate
    This HYAL1 protein is labelled with His tag.
    Purpose
    Recombinant Human Hyaluronidase-1/HYAL1 Protein (His Tag)
    Sequence
    Phe22-Trp435
    Characteristics
    Recombinant Human Hyaluronidase-1 is produced by our Mammalian expression system and the target gene encoding Phe22-Trp435 is expressed with a 6His tag at the C-terminus.
    Purity
    > 95 % as determined by reducing SDS-PAGE.
    Endotoxin Level
    < 1.0 EU per μg as determined by the LAL method.
    Top Product
    Discover our top product HYAL1 Protein
  • Restrictions
    For Research Use only
  • Format
    Frozen, Liquid
    Buffer
    Supplied as a 0.2 μm filtered solution of 20 mM TrisHCl, 150 mM NaCl, 10 % Glycerol, pH 7.5.
    Storage
    -20 °C
    Storage Comment
    Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles.
  • Target
    HYAL1 (Hyaluronidase-1 (HYAL1))
    Alternative Name
    Hyaluronidase-1/HYAL1 (HYAL1 Products)
    Synonyms
    HYAL-1 Protein, LUCA1 Protein, NAT6 Protein, Hya1 Protein, Hyal-1 Protein, hyaluronoglucosaminidase 1 Protein, HYAL1 Protein, Hyal1 Protein
    Background

    Background: Hyaluronidase-1 (HYAL1) is a secreted lysosomal hyaluronidase that belongs to the glycosyl hydrolase 56 family. HYAL1 contains one EGF-like domain and is highly expressed in the liver, kidney, and heart, but it is weakly expressed in the lung, placenta, and skeletal muscle. HYAL1 is thought to be involved in cell proliferation, migration, and differentiation. It may play a role in promoting tumor progression and blocking the TGFB1-enhanced cell growth. Mutations in HYAL1 are associated with mucopolysaccharidosis type IX, or hyaluronidase deficiency.

    Synonym: Hyaluronidase-1, Hyal-1, Hyaluronoglucosaminidase-1, Lung Carcinoma Protein 1, LuCa-1, HYAL1, LUCA1

    Molecular Weight
    47.2 kDa
    UniProt
    Q12794
    Pathways
    Glycosaminoglycan Metabolic Process
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