HAVCR1 Protein (His tag,Fc Tag)
-
- Target See all HAVCR1 Proteins
- HAVCR1 (Hepatitis A Virus Cellular Receptor 1 (HAVCR1))
- Protein Type
- Recombinant
-
Origin
- Mouse
-
Source
- HEK-293 Cells
- Purification tag / Conjugate
- This HAVCR1 protein is labelled with His tag,Fc Tag.
- Purpose
- Recombinant Mouse TIM1/HAVCR1 Protein (His & Fc Tag)
- Sequence
- Tyr 22-Thr 212
- Characteristics
- A DNA sequence encoding the extracellular domain of mouse HAVCR1 isoform b (NP_001160104.1) (Tyr 22-Thr 212) was fused with a polyhistidine tag at the C-terminus and the Fc region of human IgG1 at the N-terminus.
- Purity
- > 97 % as determined by SDS-PAGE
- Endotoxin Level
- < 1.0 EU per μg of the protein as determined by the LAL method.
- Top Product
- Discover our top product HAVCR1 Protein
-
-
- Restrictions
- For Research Use only
-
- Format
- Lyophilized
- Reconstitution
- Please refer to the printed manual for detailed information.
- Buffer
- Lyophilized from sterile 20 mM Tris-Citrate, 150 mM NaCl, pH 6.5
- Storage
- 4 °C,-20 °C,-80 °C
- Storage Comment
- Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
-
- Target
- HAVCR1 (Hepatitis A Virus Cellular Receptor 1 (HAVCR1))
- Alternative Name
- TIM1/HAVCR1 (HAVCR1 Products)
- Synonyms
- HAVCR Protein, HAVCR-1 Protein, KIM-1 Protein, KIM1 Protein, TIM Protein, TIM-1 Protein, TIM1 Protein, TIMD-1 Protein, TIMD1 Protein, Kim1 Protein, HAVCR1 Protein, LOC100226241 Protein, AI503787 Protein, Tim1 Protein, Timd1 Protein, hepatitis A virus cellular receptor 1 Protein, hepatitis A virus cellular receptor 1 homolog Protein, HAVCR1 Protein, Havcr1 Protein, LOC100226241 Protein
- Target Type
- Virus
- Background
-
Background: HAV cellular receptor 1 (HAVCR1), also known as Kidney injury molecule 1 (KIM-1) and T cell immunoglobulinmucin 1 (TIM-1), is a type â… integral membrane glycoprotein. KIM-1 protein is widely expressed with highest levels in kidney and testis. It has been shown to play a major role as a human susceptibility gene for asthma, allergy and autoimmunity. IgA1lambda is a specific ligand of KIM-1 protein and that their association has a synergistic effect in virus-receptor interactions. KIM-1 involves in the pathogenesis of acute kidney injury. It had been confirmed that KIM-1 is a human urinary renal dysfunction biomarker. Moreover, KIM-1 protein is a novel regulatory molecule of flow-induced calcium signaling.
Synonym: Hepatitis A virus cellular receptor 1 homolog; HAVcr-1; Kidney injury molecule 1; KIM-1; T cell membrane protein 1; TIM-1;Timd1;AI503787
- Molecular Weight
- 49 kDa
- NCBI Accession
- NP_001160104
-