HPGDS Protein
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- Target See all HPGDS Proteins
- HPGDS (Hematopoietic Prostaglandin D Synthase (HPGDS))
- Protein Type
- Recombinant
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Origin
- Human
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Source
- Escherichia coli (E. coli)
- Purpose
- Recombinant Human HPGDS/GSTS Protein
- Sequence
- Met 1-Leu199
- Characteristics
- Recombinant Human Hematopoietic Prostaglandin D Synthase is produced by our E.coli expression system and the target gene encoding Met1-Leu199 is expressed.
- Purity
- > 95 % as determined by reducing SDS-PAGE.
- Endotoxin Level
- < 1.0 EU per μg as determined by the LAL method.
- Top Product
- Discover our top product HPGDS Protein
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Hematopoietic Prostaglandin D Synthase (HPGDS) (AA 2-199) protein (His tag)
HPGDS Origin: Human Host: Escherichia coli (E. coli) Recombinant Greater than 95 % as determined by SDS-PAGE ELISA, WB
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- Restrictions
- For Research Use only
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- Format
- Frozen, Liquid
- Buffer
- Supplied as a 0.2 μm filtered solution of 20 mM Tris, 200 mM NaCl, pH 7.0.
- Storage
- -20 °C
- Storage Comment
- Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles.
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- Target
- HPGDS (Hematopoietic Prostaglandin D Synthase (HPGDS))
- Alternative Name
- HPGDS/GSTS (HPGDS Products)
- Synonyms
- GSTS Protein, GSTS1-1 Protein, PGD2 Protein, PGDS Protein, L-PGDS Protein, LPGDS Protein, PDS Protein, PGDS2 Protein, XlGSTS1 Protein, gsts Protein, pgds Protein, H-PGDS Protein, Ptgds2 Protein, hpgds Protein, hpgds-a Protein, hpgds-b Protein, hpgdsa Protein, hematopoietic prostaglandin D synthase Protein, prostaglandin D2 synthase Protein, hematopoietic prostaglandin D synthase L homeolog Protein, HPGDS Protein, PTGDS Protein, hpgds Protein, Hpgds Protein, hpgds.L Protein
- Background
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Background: Hematopoietic Prostaglandin D Synthase (HPGDS) belongs to the GST superfamily and Sigma family. HPGDS contains one GST C-terminal domain and one GST N-terminal domain. HPGDS is highly expressed in adipose tissue, macrophages, and placenta, and it exists in the form of homodimer in living body. HPGDS is a cytosolic enzyme that isomerizes PGH(2). HPGDS is a bifunctional enzyme that catalyzes both the conversion of PGH2 to PGD2 and also shows low glutathione-peroxidase activity towards cumenehydroperoxide.
Synonym: Hematopoietic Prostaglandin D Synthase, H-PGDS, GST Class-Sigma, Glutathione S-Transferase, Glutathione-Dependent PGD Synthase, Glutathione-Requiring Prostaglandin D Synthase, Prostaglandin-H2 D-Isomerase, HPGDS, GSTS, PGDS, PTGDS2
- Molecular Weight
- 23.6 kDa
- UniProt
- O60760
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