GAMT Protein (His tag)
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- Target See all GAMT Proteins
- GAMT (Guanidinoacetate N-Methyltransferase (GAMT))
- Protein Type
- Recombinant
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Origin
- Human
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Source
- Escherichia coli (E. coli)
- Purification tag / Conjugate
- This GAMT protein is labelled with His tag.
- Purpose
- Recombinant Human GAMT Protein (His Tag)
- Sequence
- Met 1-Gly236
- Characteristics
- Recombinant Human Guanidinoacetate N-methyltransferase is produced by our E.coli expression system and the target gene encoding Met1-Gly236 is expressed with a 6His tag at the N-terminus, 6His tag at the C-terminus.
- Purity
- > 95 % as determined by reducing SDS-PAGE.
- Endotoxin Level
- < 1.0 EU per μg as determined by the LAL method.
- Top Product
- Discover our top product GAMT Protein
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Guanidinoacetate N-Methyltransferase (GAMT) (AA 1-236) protein (His tag)
GAMT Origin: Human Host: Escherichia coli (E. coli) Recombinant Greater than 95 % as determined by SDS-PAGE WB, ELISA
Guanidinoacetate N-Methyltransferase (GAMT) (AA 138-235) protein (GST tag)GAMT Origin: Human Host: Wheat germ Recombinant WB, ELISA, AA, AP
Guanidinoacetate N-Methyltransferase (GAMT) (AA 1-236), (full length) protein (His tag)GAMT Origin: Rat Host: Escherichia coli (E. coli) Recombinant > 90 % SDS
Guanidinoacetate N-Methyltransferase (GAMT) (Transcript Variant 2) protein (Myc-DYKDDDDK Tag)GAMT Origin: Human Host: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
Guanidinoacetate N-Methyltransferase (GAMT) (Transcript Variant 1) protein (Myc-DYKDDDDK Tag)GAMT Origin: Human Host: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
Guanidinoacetate N-Methyltransferase (GAMT) (AA 1-236) protein (His tag)GAMT Origin: Rat Host: Yeast Recombinant > 90 % ELISA
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- Restrictions
- For Research Use only
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- Format
- Frozen, Liquid
- Buffer
- Supplied as a 0.2 μm filtered solution of 20 mM TrisHCl,1 mMDTT, pH 8.0 .
- Storage
- -20 °C
- Storage Comment
- Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles.
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- Target
- GAMT (Guanidinoacetate N-Methyltransferase (GAMT))
- Alternative Name
- GAMT (GAMT Products)
- Synonyms
- gamt Protein, zgc:123136 Protein, CCDS2 Protein, PIG2 Protein, TP53I2 Protein, AA571402 Protein, Spintz1 Protein, MGC75698 Protein, GAMT Protein, GMT Protein, guanidinoacetate N-methyltransferase L homeolog Protein, guanidinoacetate N-methyltransferase S homeolog Protein, guanidinoacetate N-methyltransferase Protein, guanidinoacetate methyltransferase Protein, gamt.L Protein, gamt.S Protein, gamt Protein, GAMT Protein, Gamt Protein
- Background
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Background: GAMT is a methyltransferase which belongs to the class I-like SAM-binding methyltransferase superfamily. It contains one RMT2 (arginine N-methyltransferase 2-like) domain and is expressed in liver. GAMT converts guanidoacetate to creatine, using S-adenosylmethionine as the methyl donor. Defects in GAMT are the cause of guanidinoacetate methyltransferase deficiency, which is an autosomal recessive disorder characterized by developmental delay/regression, mental retardation, severe disturbance of expressive and cognitive speech, intractable seizures and movement disturbances, severe depletion of creatine/phosphocreatine in the brain, and accumulation of guanidinoacetic acid in brain and body fluids.
Synonym: Guanidinoacetate N-methyltransferase, GAMT, PIG2,TP53I2
- Molecular Weight
- 29.5 kDa
- UniProt
- Q14353
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