GDF11 Protein
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- Target See all GDF11 Proteins
- GDF11 (Growth Differentiation Factor 11 (GDF11))
- Protein Type
- Recombinant
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Origin
- Human
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Source
- Human Cells
- Purpose
- Recombinant Human GDF11/BMP-11 Protein
- Sequence
- Asn299-Ser407
- Characteristics
- Recombinant Human Growth differentiation factor 11 is produced by our Mammalian expression system and the target gene encoding Asn299-Ser407 is expressed.
- Purity
- > 95 % as determined by reducing SDS-PAGE.
- Endotoxin Level
- < 1.0 EU per μg as determined by the LAL method.
- Top Product
- Discover our top product GDF11 Protein
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Growth Differentiation Factor 11 (GDF11) (AA 310-407) protein (GST tag)
GDF11 Origin: Human Host: Wheat germ Recombinant WB, ELISA, AA, AP
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- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Please refer to the printed manual for detailed information.
- Buffer
- Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4.
- Storage
- 4 °C,-20 °C,-80 °C
- Storage Comment
- Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
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- Target
- GDF11 (Growth Differentiation Factor 11 (GDF11))
- Alternative Name
- GDF11/BMP-11 (GDF11 Products)
- Synonyms
- BMP-11 Protein, BMP11 Protein, Bmp11 Protein, GDF11 Protein, growth differentiation factor 11 Protein, GDF11 Protein, Gdf11 Protein, gdf11 Protein
- Background
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Background: Growth/differentiation factor 11(GDF-11) is a secreted protein, which belongs to the transforming growth factor beta superfamily. GDF-11 controls anterior-posterior patterning by regulating the expression of Hox genes. The secreted signal acts globally to specify positional identity along the anterior/posterior axis during development. GDF11 has been shown to suppress neurogenesis through a pathway similar to that of myostatin, including stopping the progenitor cell-cycle during G-phase. The similarities between GDF11 and myostatin imply a likelihood that the same regulatory mechanisms are used to control tissue size during both muscular and neural development.
Synonym: Growth/differentiation factor 11,GDF-11,Bone morphogenetic protein 11,BMP-11
- Molecular Weight
- 12.6 kDa
- UniProt
- O95390
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