Granzyme D Protein (GZMD) (His tag)

Catalog No. ABIN7320541

Product Details

Target: Granzyme D (GZMD)

Protein Type: Recombinant

Origin: Mouse

Source: Human Cells

Purification tag / Conjugate: This Granzyme D protein is labelled with His tag.

Purpose: Recombinant Mouse Granzyme D/GZMD Protein (His Tag)

Sequence: Ile21-Leu252

Characteristics: Recombinant Mouse Granzyme D is produced by our Mammalian expression system and the target gene encoding Ile21-Leu252 is expressed with a 6His tag at the C-terminus.

Purity: > 90 % as determined by SDS-PAGE

Endotoxin Level: < 1.0 EU per μg as determined by the LAL method.

Application Details

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Please refer to the printed manual for detailed information.

Buffer: Lyophilized from a 0.2 μm filtered solution of 20 mM HEPES, 150 mM NaCl, pH 7.4.

Storage: 4 °C,-20 °C,-80 °C

Storage Comment: Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.

Target Details

Target: Granzyme D (GZMD)

Alternative Name: Granzyme D/GZMD (GZMD Products)

Synonyms: CCP5 Protein, Ctla-5 Protein, Ctla5 Protein, granzyme D Protein, Gzmd Protein

Background:

Background: Granzyme D is a member of the granzyme family of the serine proteases which plays a role in the induction of apoptosis. T cells, lymphohematopoietic stromal cells, and granulated metrial gland cells express granzyme D, but the function of granzyme D is unknown. Previous studies reported that granzyme D is developmentally regulated during pregnancy together with granzymes E, F, and G in granulated metrial gland cells and is upregulated by IL-2 and IL-15. Granzyme D was also suggested to have a role in stromal cell-lymphocyte interactions.

Synonym: Granzyme D, Gzmd

Molecular Weight: 26.8 kDa

UniProt: P11033