Grancalcin Protein
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- Target See all Grancalcin (GCA) Proteins
- Grancalcin (GCA) (Grancalcin, EF-Hand Calcium Binding Protein (GCA))
- Protein Type
- Recombinant
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Origin
- Human
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Source
- Escherichia coli (E. coli)
- Purpose
- Recombinant Human Grancalcin/GCA Protein
- Sequence
- Met 1-Ile217
- Characteristics
- Recombinant Human Grancalcin is produced by our E.coli expression system and the target gene encoding Met1-Ile217 is expressed.
- Purity
- > 95 % as determined by reducing SDS-PAGE.
- Endotoxin Level
- < 1.0 EU per μg as determined by the LAL method.
- Top Product
- Discover our top product GCA Protein
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- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Please refer to the printed manual for detailed information.
- Buffer
- Lyophilized from a 0.2 μm filtered solution of 20 mM TrisHCl, 150 mM NaCl, 1 mM EDTA, pH 8.5.
- Storage
- 4 °C,-20 °C,-80 °C
- Storage Comment
- Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
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- Target
- Grancalcin (GCA) (Grancalcin, EF-Hand Calcium Binding Protein (GCA))
- Alternative Name
- Grancalcin/GCA (GCA Products)
- Synonyms
- Grancalcin Protein, 5133401E04Rik Protein, AI573844 Protein, GCL Protein, zgc:92027 Protein, grancalcin Protein, Grancalcin Protein, zgc:92027 Protein, GCA Protein, gran Protein, LOC100280890 Protein, Gca Protein
- Background
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Background: Grancalcin (GCA) is a cytoplasmic granule membrane protein that contains 4 EF-hand domains. GCA is calcium-binding protein and particularly abundant in human neutrophils. GCA is highly expressed in bone marrow, and it can be detected in neutrophils and macrophages. Calcium-binding protein GCA cooperates with SRI and LCP1, so it may play a role in the adhesion of neutrophils to fibronectin. GCA also may play a role in the formation of focal adhesions.
Synonym: Grancalcin, GCA, GCL
- Molecular Weight
- 24.0 kDa
- UniProt
- P28676
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