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Glutathione Synthetase Protein (GSS) (His tag)

GSS Origin: Human Host: Escherichia coli (E. coli) Recombinant > 95 % as determined by reducing SDS-PAGE.
Catalog No. ABIN7318542
  • Target See all Glutathione Synthetase (GSS) Proteins
    Glutathione Synthetase (GSS)
    Protein Type
    Recombinant
    Origin
    • 6
    • 3
    • 2
    • 1
    • 1
    • 1
    Human
    Source
    • 8
    • 4
    • 1
    • 1
    Escherichia coli (E. coli)
    Purification tag / Conjugate
    This Glutathione Synthetase protein is labelled with His tag.
    Purpose
    Recombinant Human GSS Protein (His Tag)
    Sequence
    Ala2-Val474
    Characteristics
    Recombinant Human Glutathione Synthetase is produced by our E.coli expression system and the target gene encoding Ala2-Val474 is expressed with a 6His tag at the C-terminus.
    Purity
    > 95 % as determined by reducing SDS-PAGE.
    Endotoxin Level
    < 1.0 EU per μg as determined by the LAL method.
    Top Product
    Discover our top product GSS Protein
  • Restrictions
    For Research Use only
  • Format
    Frozen, Liquid
    Buffer
    Supplied as a 0.2 μm filtered solution of 20 mM TrisHCl, 200 mM NaCl, pH 7.5 .
    Storage
    -20 °C
    Storage Comment
    Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles.
  • Target
    Glutathione Synthetase (GSS)
    Alternative Name
    GSS (GSS Products)
    Synonyms
    PRNP Protein, 6835 Protein, CG32497 Protein, CG33065 Protein, CG6835 Protein, Dmel\\CG6835 Protein, F21A20.90 Protein, F21A20_90 Protein, GLUTATHIONE SYNTHETASE Protein, GSHB Protein, glutathione synthetase 2 Protein, GSHS Protein, AI314904 Protein, GS-A/GS-B Protein, gssls-a Protein, glutathione synthetase Protein, Glutathione Synthetase Protein, glutathione synthetase 2 Protein, glutathione synthetase L homeolog Protein, GSS Protein, GSH2 Protein, Tola_1250 Protein, PC1_3711 Protein, Dd586_3633 Protein, Kvar_0701 Protein, Alvin_0197 Protein, Nhal_0215 Protein, BC1002_0254 Protein, Cseg_4017 Protein, Snov_3844 Protein, Aazo_1904 Protein, M301_2613 Protein, Bresu_0515 Protein, Isop_1460 Protein, Marme_4020 Protein, Thicy_0325 Protein, Sinme_3668 Protein, Mesop_0757 Protein, Gss Protein, gss.L Protein
    Background

    Background: Glutathione Synthetase belongs to the eukaryotic GSH synthase family. Glutathione Synthetase is the second enzyme in the glutathione biosynthesis pathway. It catalyses the condensation of gamma-glutamylcysteine and glycine to form glutathione. Glutathione play an important role in a variety of biological functions, including detoxification of xenobiotics, protection of cells from oxidative damage by free radicals, and membrane transport. The protein functions as a homodimer to catalyze the second step of glutathione biosynthesis, which is the ATP-dependent conversion of gamma-L-glutamyl-L-cysteine to glutathione. Defects in Glutathione Synthetase can also cause the glutathione synthetase deficiency of erythrocytes, which is a mild form causing hemolytic anemia.

    Synonym: Glutathione Synthetase, GSH Synthetase, GSH-S, Glutathione Synthase, GSS

    Molecular Weight
    53.5 kDa
    UniProt
    P48637
    Pathways
    Warburg Effect
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