GSTP1 Protein
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- Target See all GSTP1 Proteins
- GSTP1 (Glutathione S-Transferase pi 1 (GSTP1))
- Protein Type
- Recombinant
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Origin
- Human
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Source
- Escherichia coli (E. coli)
- Purpose
- Recombinant Human GSTP1 Protein
- Sequence
- Met 1-Glu210
- Characteristics
- Recombinant Human Glutathione S-Transferase pi 1 is produced by our E.coli expression system and the target gene encoding Met1-Glu210 is expressed.
- Purity
- > 95 % as determined by reducing SDS-PAGE.
- Endotoxin Level
- < 1.0 EU per μg as determined by the LAL method.
- Top Product
- Discover our top product GSTP1 Protein
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Glutathione S-Transferase pi 1 (GSTP1) (AA 1-210) protein (GST tag)
GSTP1 Origin: Human Host: Wheat germ Recombinant WB, ELISA, AP, AA
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- Restrictions
- For Research Use only
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- Format
- Frozen, Liquid
- Buffer
- Supplied as a 0.2 μm filtered solution of 20 mM Tris,150 mM NaCl,10 % Glycerol, pH 8.0.
- Storage
- -20 °C
- Storage Comment
- Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles.
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- Target
- GSTP1 (Glutathione S-Transferase pi 1 (GSTP1))
- Alternative Name
- GSTP1 (GSTP1 Products)
- Synonyms
- DFN7 Protein, FAEES3 Protein, GST3 Protein, GSTP Protein, PI Protein, GST-P Protein, Gst3 Protein, Gstp Protein, Gstp2 Protein, gst-Pi Protein, GstpiB Protein, glutathione S-transferase P-like Protein, glutathione S-transferase pi 1 Protein, glutathione S-transferase pi 1 L homeolog Protein, glutathione S-transferase, pi 1 Protein, LOC100739163 Protein, GSTP1 Protein, Gstp1 Protein, LOC100861197 Protein, gstp1.L Protein
- Background
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Background: Glutathione S-transferase P (GSTP1) is an enzyme that contains 1 GST C-terminal domain, 1 GST N-terminal domain. GSTP1 belongs to the GST superfamily, the GSTs are a family of enzymes that play an important role in detoxification by catalyzing the conjugation of many hydrophobic and electrophilic compounds with reduced glutathione. Based on their biochemical, immunologic, and structural properties, the soluble GSTs are categorized into 4 main classes: alpha, mu, pi, and theta. The glutathione S-transferase pi gene (GSTP1) is a polymorphic gene encoding active, functionally different GSTP1 variant proteins. Besides, it regulates negatively CDK5 activity via p25/p35 translocation to prevent neurodegeneration. It thought to function in xenobiotic metabolism and play a role in susceptibility to cancer, and other diseases.
Synonym: Glutathione S-transferase P,GSTP1,GST class-pi,GSTP1-1,FAEES3,GST3,
- Molecular Weight
- 23.5 kDa
- UniProt
- P09211
- Pathways
- Cellular Response to Molecule of Bacterial Origin
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