GCDH Protein (His tag)
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- Target See all GCDH Proteins
- GCDH (Glutaryl-CoA Dehydrogenase (GCDH))
- Protein Type
- Recombinant
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Origin
- Human
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Source
- Escherichia coli (E. coli)
- Purification tag / Conjugate
- This GCDH protein is labelled with His tag.
- Purpose
- Recombinant Human GCDH Protein (His Tag)
- Sequence
- Arg45-Lys438
- Characteristics
- Recombinant Human Glutaryl-CoA Dehydrogenase, Mitochondrial is produced by our E.coli expression system and the target gene encoding Arg45-Lys438 is expressed with a 6His tag at the N-terminus.
- Purity
- > 95 % as determined by reducing SDS-PAGE.
- Endotoxin Level
- < 1.0 EU per μg as determined by the LAL method.
- Top Product
- Discover our top product GCDH Protein
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- Restrictions
- For Research Use only
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- Format
- Frozen, Liquid
- Buffer
- Supplied as a 0.2 μm filtered solution of 20 mM HEPES, 150 mM NaCl, pH 7.4.
- Storage
- -20 °C
- Storage Comment
- Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles.
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- Target
- GCDH (Glutaryl-CoA Dehydrogenase (GCDH))
- Alternative Name
- GCDH (GCDH Products)
- Synonyms
- ACAD5 Protein, GCD Protein, zgc:56505 Protein, zgc:77704 Protein, 9030411L18 Protein, AI266902 Protein, D17825 Protein, glutaryl-CoA dehydrogenase Protein, glutaryl-CoA dehydrogenase a Protein, glutaryl-Coenzyme A dehydrogenase Protein, GCDH Protein, Gcdh Protein, gcdha Protein
- Background
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Background: Glutaryl-CoA Dehydrogenase Mitochondrial (GCDH) is an enzyme that acts upon glutaryl-coenzyme A, creating crotonyl-coenzyme A. It plays a role in the metabolism of lysine, hydroxylysine and tryptophan. It uses electron transfer flavoprotein as its electron acceptor. Isoform Short is inactive Glutaryl-CoA and electron-transfer flavoprotein to (E)-but-2-enoyl-CoA, CO2 and reduced electron-transfer flavoprotein. A defect in this enzyme is associated with neurological condition glutaric acidemia type 1 and cause a progressive form of early-onset generalized dystonia.
Synonym: Glutaryl-CoA Dehydrogenase Mitochondrial, GCD, GCDH
- Molecular Weight
- 45.0 kDa
- UniProt
- Q92947
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