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FH Protein

FH Origin: Human Host: Escherichia coli (E. coli) Recombinant > 95 % as determined by reducing SDS-PAGE.
Catalog No. ABIN7318507
  • Target See all FH Proteins
    FH (Fumarate Hydratase (FH))
    Protein Type
    Recombinant
    Origin
    • 6
    • 1
    • 1
    • 1
    • 1
    Human
    Source
    • 5
    • 3
    • 1
    • 1
    Escherichia coli (E. coli)
    Purpose
    Recombinant Human Fumarase/FH Protein
    Sequence
    Ala45-Lys510
    Characteristics
    Recombinant Human Fumarase is produced by our E.coli expression system and the target gene encoding Ala45-Lys510 is expressed.
    Purity
    > 95 % as determined by reducing SDS-PAGE.
    Endotoxin Level
    < 1.0 EU per μg as determined by the LAL method.
    Top Product
    Discover our top product FH Protein
  • Restrictions
    For Research Use only
  • Format
    Frozen, Liquid
    Buffer
    Supplied as a 0.2 μm filtered solution of 20 mM Tris, pH 8.0.
    Storage
    -20 °C
    Storage Comment
    Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles.
  • Target
    FH (Fumarate Hydratase (FH))
    Alternative Name
    Fumarase/FH (FH Products)
    Synonyms
    FH Protein, DDBDRAFT_0205237 Protein, DDBDRAFT_0231397 Protein, DDBDRAFT_0231400 Protein, DDB_0205237 Protein, DDB_0231397 Protein, DDB_0231400 Protein, HLRCC Protein, LRCC Protein, MCL Protein, MCUL1 Protein, Fh1 Protein, im:7152785 Protein, ns:zf-e152 Protein, zf-e152 Protein, zgc:66253 Protein, zgc:77498 Protein, Fh Protein, Fh-1 Protein, fumarate hydratase Protein, fumarate hydratase 1 Protein, FH Protein, fumH Protein, Fh Protein, fh Protein, Fh1 Protein
    Background

    Background: Fumarase is an enzyme that catalyze the reversible hydration/dehydration of fumarate to S-malate and is involved in the tricarboxylic acid or Krebs cycle. Fumarase exists in both form, cytosolic formand N-terminal extend mitochondrial form. The N-terminal extended form is targeted to the mitochondrion, where the removal of the extension is the same form as in the cytoplasm. Fumarase is thought to act as a tumor suppressor, which deficiency can lead to progressive encephalopathy, cerebral atrophy and development delay.

    Synonym: Fumarate Hydratase Mitochondrial, Fumarase, FH,FMRD,HLRCC,LRCC,MCL,MCUL1

    Molecular Weight
    50.2 kDa
    UniProt
    P07954
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