FZD4 Protein (His tag)
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- Target See all FZD4 Proteins
- FZD4 (Frizzled Family Receptor 4 (FZD4))
- Protein Type
- Recombinant
- Origin
- Human
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Source
- HEK-293 Cells
- Purification tag / Conjugate
- This FZD4 protein is labelled with His tag.
- Purpose
- Recombinant Human Frizzled-4/FZD4 Protein (His Tag)
- Sequence
- Met 1-Glu180
- Characteristics
- A DNA sequence encoding the human FZD4 (NP_036325.2) (Met1-Glu180) was expressed with a polyhistidine tag at the C-terminus.
- Purity
- > 95 % as determined by reducing SDS-PAGE.
- Endotoxin Level
- < 1.0 EU per μg of the protein as determined by the LAL method.
- Top Product
- Discover our top product FZD4 Protein
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- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Please refer to the printed manual for detailed information.
- Buffer
- Lyophilized from sterile PBS, pH 7.4
- Storage
- 4 °C,-20 °C,-80 °C
- Storage Comment
- Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
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- Target
- FZD4 (Frizzled Family Receptor 4 (FZD4))
- Alternative Name
- Frizzled-4/FZD4 (FZD4 Products)
- Synonyms
- CG4626 Protein, DFz4 Protein, Dfz4 Protein, Dm Fz4 Protein, Dmel\\CG4626 Protein, Fz4 Protein, anon-WO0170980.10 Protein, anon-WO0170980.11 Protein, fz1 Protein, zg01 Protein, CD344 Protein, EVR1 Protein, FEVR Protein, FZD4S Protein, Fz-4 Protein, FzE4 Protein, GPCR Protein, hFz4 Protein, frizzled4 Protein, fz4 Protein, FZ-4 Protein, frizzled 4 Protein, frizzled class receptor 4 Protein, frizzled-4 Protein, frizzled class receptor 4 S homeolog Protein, fz4 Protein, fzd4 Protein, Tsp_10376 Protein, FZD4 Protein, Fzd4 Protein, fzd4.S Protein
- Background
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Background: This gene is a member of the frizzled gene family. Members of this family encode seven-transmembrane domain proteins that are receptors for the Wingless type MMTV integration site family of signaling proteins. Most frizzled receptors are coupled to the beta-catenin canonical signaling pathway. This protein may play a role as a positive regulator of the Wingless type MMTV integration site signaling pathway. A transcript variant retaining intronic sequence and encoding a shorter isoform has been described, however, its expression is not supported by other experimental evidence.
Synonym: CD344,EVR1,FEVR,Fz-4,Fz4,FZD4S,FzE4,GPCR,hFz4
- Molecular Weight
- 17.7 kDa
- NCBI Accession
- NP_036325
- Pathways
- WNT Signaling, Hormone Transport, Sensory Perception of Sound
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