FKBP4 Protein (His tag)
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- Target See all FKBP4 Proteins
- FKBP4 (FK506 Binding Protein 4, 59kDa (FKBP4))
- Protein Type
- Recombinant
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Origin
- Human
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Source
- Escherichia coli (E. coli)
- Purification tag / Conjugate
- This FKBP4 protein is labelled with His tag.
- Purpose
- Recombinant Human FKBP4 Protein (His Tag)
- Sequence
- Met 1-Ala459
- Characteristics
- Recombinant Human 52 kDa FK506 Binding Protein is produced by our E.coli expression system and the target gene encoding Met1-Ala459 is expressed with a 6His tag at the C-terminus.
- Purity
- > 95 % as determined by reducing SDS-PAGE.
- Endotoxin Level
- < 1.0 EU per μg as determined by the LAL method.
- Top Product
- Discover our top product FKBP4 Protein
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- Restrictions
- For Research Use only
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- Format
- Frozen, Liquid
- Buffer
- Supplied as a 0.2 μm filtered solution of 20 mM Tris,10 % glycerol, pH 8.0.
- Storage
- -20 °C
- Storage Comment
- Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles.
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- Target
- FKBP4 (FK506 Binding Protein 4, 59kDa (FKBP4))
- Alternative Name
- FKBP4 (FKBP4 Products)
- Synonyms
- HBI Protein, p52 Protein, hsp56 Protein, PPIase Protein, fkbp52 Protein, fkbp59 Protein, MGC81078 Protein, wu:fb34f09 Protein, 59kDa Protein, AL022792 Protein, AW208983 Protein, FKBP-4 Protein, FKBP-52 Protein, FKBP52 Protein, FKPB52 Protein, p59 Protein, FKBP51 Protein, FKBP59 Protein, Hsp56 Protein, P59 Protein, FK506 binding protein 4 Protein, FK506 binding protein 4 S homeolog Protein, FKBP4 Protein, fkbp4.S Protein, fkbp4 Protein, Fkbp4 Protein
- Background
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Background: FKBP4 act as a regulator of microtubule dynamics by inhibiting MAPT/TAU ability to promote microtubule assembly. FKBP4 may play a role in the intracellular trafficking of heterooligomeric forms of steroid hormone receptors between cytoplasm and nuclear compartments, it also may have a protective role against oxidative stress in mitochondria. The isomerase activity controls neuronal growth cones via regulation of TRPC1 channel opening.
Synonym: Peptidyl-prolyl cis-trans isomerase FKBP4, 51 kDa FK506-binding protein, 51 kDa FK506-binding protein, 59 kDa immunophilin, FK506-binding protein 4, FKBP59, HSP-binding immunophilin, immunophilin FKBP52, Rotamase, FKBP4
- Molecular Weight
- 52.8 kDa
- UniProt
- Q02790
- Pathways
- Intracellular Steroid Hormone Receptor Signaling Pathway
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