EPH Receptor A4 Protein (EPHA4)

Catalog No. ABIN7318103

Product Details

Target: EPH Receptor A4 (EPHA4)

Protein Type: Recombinant

Origin: Human

Source: Human Cells

Purpose: Recombinant Human EphA4 Protein

Sequence: Val20-Thr547

Characteristics: Recombinant Human Ephrin type-A receptor 4 is produced by our Mammalian expression system and the target gene encoding Val20-Thr547 is expressed.

Purity: > 95 % as determined by reducing SDS-PAGE.

Endotoxin Level: < 1.0 EU per μg as determined by the LAL method.

Application Details

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Please refer to the printed manual for detailed information.

Buffer: Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4.

Storage: 4 °C,-20 °C,-80 °C

Storage Comment: Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.

Target Details

Target: EPH Receptor A4 (EPHA4)

Alternative Name: EphA4 (EPHA4 Products)

Background:

Background: Ephrin type-A receptor 4(EPHA4) belongs to the protein kinase superfamily and Ephrin receptor subfamily. EPHA4 contains 1 Eph LBD domain, 2 fibronectin type-III domains, 1 protein kinase domain and 1 SAM domain. EPH and EPH-related receptors have been implicated in mediating developmental events, particularly in the nervous system. Receptors in the EPH subfamily typically have a single kinase domain and an extracellular region containing a Cys-rich domain and 2 fibronectin type III repeats. The ephrin receptors are divided into 2 groups based on the similarity of their extracellular domain sequences and their affinities for binding ephrin-A and ephrin-B ligands.

Synonym: Ephrin type-A receptor 4,HEK8, SEK, TYRO1,EPHA4,Tyrosine-protein kinase receptor SEK,Tyrosine-protein kinase TYRO1,EK8,hEK8,EPH-like kinase 8

Molecular Weight: 59.2 kDa

UniProt: P54764

Pathways: RTK Signaling