ENTPD2 Protein (His tag)
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- Target See all ENTPD2 Proteins
- ENTPD2 (Ectonucleoside Triphosphate diphosphohydrolase 2 (ENTPD2))
- Protein Type
- Recombinant
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Origin
- Mouse
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Source
- Human Cells
- Purification tag / Conjugate
- This ENTPD2 protein is labelled with His tag.
- Purpose
- Recombinant Mouse NTPDase 2/ENTPD2 Protein (His Tag)
- Sequence
- Cys26-Ser462
- Characteristics
- Recombinant Mouse ENTPD2 is produced by our Mammalian expression system and the target gene encoding Cys26-Ser462 is expressed with a 6His tag at the C-terminus.
- Purity
- > 95 % as determined by reducing SDS-PAGE.
- Endotoxin Level
- < 1.0 EU per μg as determined by the LAL method.
- Top Product
- Discover our top product ENTPD2 Protein
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- Restrictions
- For Research Use only
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- Format
- Frozen, Liquid
- Buffer
- Supplied as a 0.2 μm filtered solution of 50 mM Tris,10 mM CaCl2,150 mMNaCl,10 % Glycerol, pH 7.5 .
- Storage
- -20 °C
- Storage Comment
- Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles.
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- Target
- ENTPD2 (Ectonucleoside Triphosphate diphosphohydrolase 2 (ENTPD2))
- Alternative Name
- NTPDase 2/ENTPD2 (ENTPD2 Products)
- Synonyms
- MGC76207 Protein, MGC151796 Protein, CD39L1 Protein, NTPDase-2 Protein, Cd39l1 Protein, NTPDase2 Protein, ectonucleoside triphosphate diphosphohydrolase 2 Protein, Ectonucleoside triphosphate diphosphohydrolase 2 Protein, entpd2 Protein, ENTPD2 Protein, enp2 Protein, Entpd2 Protein
- Background
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Background: CD39L1 protein (ENTPD2 or NTPDase2) is a member of the ecto-nucleoside triphosphate diphosphohydrolase family which the main role is termination of purinergic signaling. CD39L1 gene encodes a precursor protein with 495 amino acid residues which generates a 437 amino acid residues mature protein after processing. It is an ecto-nucleotidase that found on the surface of vascular adventitial cells and accessory vascular cells. CD39L1 is a Ca2+- and Mg2+-dependent enzyme that activates platelets by preferentially converting ATP to ADP. CD39L1 plays a role in regulating thrombosis and inflammation which is considered to be a therapeutic target for thromboregulation and the treatment of vascular inflammation. Alternative splicing of CD39L1 gene results in multiple transcript variants.
Synonym: Ectonucleoside triphosphate diphosphohydrolase 2, Entpd2, Ecto-Nucleoside Triphosphate Diphosphohydrolase 2
- Molecular Weight
- 49.2 kDa
- UniProt
- O55026
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