DPEP2 Protein (His tag)
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- Target See all DPEP2 Proteins
- DPEP2 (Dipeptidase 2 (DPEP2))
- Protein Type
- Recombinant
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Origin
- Human
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Source
- HEK-293 Cells
- Purification tag / Conjugate
- This DPEP2 protein is labelled with His tag.
- Purpose
- Recombinant Human DPEP2 Protein (His Tag)
- Sequence
- Met 1-Ser376
- Characteristics
- A DNA sequence encoding the human DPEP2 (AAH24021.1) (Met1-Ser376) was expressed with a polyhistidine tag at the C-terminus.
- Purity
- > 90 % as determined by reducing SDS-PAGE.
- Endotoxin Level
- < 1.0 EU per μg as determined by the LAL method.
- Top Product
- Discover our top product DPEP2 Protein
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- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Please refer to the printed manual for detailed information.
- Buffer
- Lyophilized from sterile PBS, pH 7.4
- Storage
- 4 °C,-20 °C,-80 °C
- Storage Comment
- Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
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- Target
- DPEP2 (Dipeptidase 2 (DPEP2))
- Alternative Name
- DPEP2 (DPEP2 Products)
- Synonyms
- DIP-2 Protein, F630103D06Rik Protein, MBD-2 Protein, MBD2 Protein, dipeptidase 3 Protein, dipeptidase 2 Protein, Dipeptidase 2 Protein, DPEP3 Protein, LOC539370 Protein, LOC611083 Protein, DPEP2 Protein, Dip-2 Protein, Dpep2 Protein
- Background
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Background: DPEP2 (MBD-2) belongs to the membrane-bound dipeptidase family. There are three members of this family as membrane-bound dipeptidase-1 (MBD-1),membrane-bound dipeptidase-2 (MBD-2) and membrane-bound dipeptidase-3 (MBD-3).MBD-2 is expressed at highest levels in lung, heart, and testis and at some what lower levels in spleen.MBD-2 is membrane-bound through a glycosylphosphatidyl-inositol linkage and probably is a metalloprotease which hydrolyzes leukotriene D4 (LTD4) into leukotriene E4 (LTE4).It is generally recognized that rapid cleavage of LTD4 is important in inactivating the broncho-and vaso-constrictive effects of cysteinyl LTs in asthmatic and inflammatory processes.
Synonym: MBD2
- Molecular Weight
- 39.4 kDa
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