DCK Protein (T7 tag,His tag)
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- Target See all DCK Proteins
- DCK (Deoxycytidine Kinase (DCK))
- Protein Type
- Recombinant
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Origin
- Human
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Source
- Escherichia coli (E. coli)
- Purification tag / Conjugate
- This DCK protein is labelled with T7 tag,His tag.
- Purpose
- Recombinant Human Deoxycytidine Kinase/DCK Protein (His &T7 Tag)
- Sequence
- Met 1-Leu260
- Characteristics
- Recombinant Human Deoxycytidine Kinase is produced by our E.coli expression system and the target gene encoding Met1-Leu260 is expressed with a 6His, T7 tag at the N-terminus.
- Purity
- > 90 % as determined by reducing SDS-PAGE.
- Endotoxin Level
- < 1.0 EU per μg as determined by the LAL method.
- Top Product
- Discover our top product DCK Protein
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- Restrictions
- For Research Use only
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- Format
- Frozen, Liquid
- Buffer
- Supplied as a 0.2 μm filtered solution of 20 mM TrisHCl, pH 7.5.
- Storage
- -20 °C
- Storage Comment
- Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles.
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- Target
- DCK (Deoxycytidine Kinase (DCK))
- Alternative Name
- Deoxycytidine Kinase/DCK (DCK Products)
- Synonyms
- dck Protein, DCK Protein, wu:fc15f06 Protein, zgc:101771 Protein, dck1 Protein, deoxycytidine kinase Protein, deoxycytidine kinase, gene 2 L homeolog Protein, deoxycytidine kinase, gene 2 Protein, Deoxycytidine kinase Protein, deoxycytidine kinase, gene 1 L homeolog Protein, DCK Protein, dck Protein, dck.2.L Protein, dck.2 Protein, Dck Protein, FPV059 Protein, FPV151 Protein, dck.1.L Protein
- Background
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Background: Deoxycytidine Kinase (DCK) is a member of the DCK/DGK family. DCK exists as a homodimer and is localized to the nucleus. DCK is required for the phosphorylation of the deoxyribonucleosides deoxycytidine (dC), deoxyguanosine (dG), and deoxyadenosine (dA). DCK has broad substrate specificity, and does not display selectivity based on the chirality of the substrate. In addition, DCK is also an essential enzyme for the phosphorylation of numerous nucleoside analogs widely employed as antiviral and chemotherapeutic agents. DCK is clinically important because of its relationship to drug resistance and sensitivity.
Synonym: Deoxycytidine Kinase, dCK, DCK
- Molecular Weight
- 34.0 kDa
- UniProt
- P27707
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